Lymphoma Monocyte Crosstalk Via Hsp27 to Promote Immune Suppression and Chemotherapy Resistance

• Published in: Blood Vol. 124; no. 21; p. 2966
• Main Authors: Zhang, Zhe, Bulur, Peggy A, Gustafson, Michael, Gastineau, Dennis A., Dietz, Allan B, Lin, Yi
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 06.12.2014

Background: Immune editing is a major mechanism used by tumors to promote its survival. We have reported previously the presence of a novel phenotype of immunosuppressive monocytes (CD14+HLA-DRlow/neg) in a number of cancers. Increased presence of these cells was associated with decreased treatment...