Compensatory Signaling From ROR1 and the Pre-B Cell Receptor Promote Survival of t(1;19) Acute Lymphoblastic Leukemia

• Published in: Blood Vol. 118; no. 21; p. 2466
• Main Authors: Bicocca, Vincent T, Chang, Bill H, Muschen, Markus, Druker, Brian J., Tyner, Jeffrey W
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 18.11.2011

Abstract▪2466▪This icon denotes a clinically relevant abstract Aberrant tyrosine kinase activity is commonly implicated in the pathogenesis of leukemia and other cancers. Identification of these leukemogenic tyrosine kinases has proven invaluable for diagnostic and prognostic stratification of patie...