A suspected case of Progressive Familial Intra-hepatic Cholestasis in a Six-Year-Old Nigerian Child

• Published in: Annals of Health Research (Onabanjo University Teaching Hospital) Vol. 5; no. 1; pp. 135 - 140
• Main Authors: Atimati, Anthony Oyovwikigho, Ikhurionan, Paul
• Format: Journal Article
• Language: English
• Published: Medical and Dental Consultants Association of Nigeria, OOUTH Sagamu 01.06.2019
• Subjects: Childhood; Conjugated hyperbilirubinaemia; Progressive Familial Intra-hepatic Cholestasis; Pruritus; Ursodeoxycholic acid

Progressive Familial Intra-hepatic Cholestasis (PFIC) is a group of heterogeneous, autosomal recessive disorders characterized by cholestasis, jaundice and mutilating pruritus, mostly in infancy. The incidence of PFIC ranges from 1:50,000 to 1:100,000. There are three subtypes; Types 1 and 2 typical...