The Role of Rab38 in Rat and Human Platelet Function Defects

• Published in: Blood Vol. 108; no. 11; p. 3912
• Main Authors: Datta, Yvonne H., Rangel-Filho, Artur, Wu, Francisca C., Stephens, Kenyatta W.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 16.11.2006

The fawn-hooded hypertensive (FHH) rat is a model of a moderate platelet function defect manifest by severely prolonged tail bleeding times, decreased platelet aggregation to ADP and collagen, and decreased ADP release from dense granules. The FHH rat has a mutation at the ATG start site of the gene...