Strong Correlation of High Endogenous Plasma Levels of Tissue Factor Pathway Inhibitor (TFPI) with Poor Blood Clotting and Corrective Action of BAX 513 Under FVIII-Inhibited Conditions

• Published in: Blood Vol. 118; no. 21; p. 1201
• Main Authors: Dockal, Michael, Gorczyca, Monika, Knappe, Sabine, Palige, Michael, Ehrlich, Hartmut J., Scheiflinger, Friedrich, Jilma, Bernd
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 18.11.2011

Abstract 1201▪▪This icon denotes a clinically relevant abstract TFPI is the major physiological inhibitor of the extrinsic pathway of blood coagulation. Thus, blocking TFPI activity is a possible approach to treat bleeding disorders such as hemophilia A and B. BAX 513, a fucoidan derived from the br...