Efavirenz challenge in patients with nevirapine induced Stevens-Johnson Syndrome

• Published in: Southern African journal of infectious diseases Vol. 31; no. 4; pp. 119 - 121
• Main Authors: Manzini, Thandekile C., Gosnell, Bernadett I., John, Melanie-Anne A., Moosa, Mahomed Y. S.
• Format: Journal Article
• Language: English
• Published: AOSIS 31.12.2016
• Subjects: efavirenz; nevirapine; stevens-johnson syndrome

Background: Non-nucleoside reverse transcriptase inhibitors (NNRTI) are recommended as part of first-line treatment by the World Health Organisation (WHO) for antiretroviral treatment (ART) naïve subjects. Due to reports of cross-toxicity between nevirapine (NVP) and efavirenz (EFV), there is reluct...