Safety and Tolerability of GalNAc 3 -Conjugated Antisense Drugs Compared to the Same-Sequence 2'- O -Methoxyethyl-Modified Antisense Drugs: Results from an Integrated Assessment of Phase 1 Clinical Trial Data - Baker, Brenda F; Xia, Shuting; Partridge, Wesley; Engelhardt, Jeffery A; Tsimikas, Sotirios; Crooke, Stanley T; Bhanot, Sanjay; Geary, Richard S (Nucleic acid therapeutics, 2024)
Keywords: Acetylgalactosamine; Hepatocytes; Humans; Oligonucleotides, Antisense - genetics; RNA; GalNAc3; antisense drug; 2′MOE; ligand-conjugated antisense; triantennary N-acetylgalactosamine