Notch signaling pathway in keloid disease: Enhanced fibroblast activity in a J agged‐1 peptide‐dependent manner in lesional vs. extralesional fibroblasts

• Published in: Wound repair and regeneration Vol. 20; no. 5; pp. 688 - 706
• Main Authors: Syed, Farhatullah, Bayat, Ardeshir
• Format: Journal Article
• Language: English
• Published: 01.09.2012

Abstract Keloid disease ( KD ) is a fibroproliferative disorder of unknown etiopathogenesis with ill‐defined treatment. There is increasing evidence to suggest that aberrant N otch signaling may contribute directly to skin pathogenesis and altered expression of N otch receptors identified in KD . Th...