Mesenchymal stem cells educate breast tumor associated macrophages to acquire increased immunosuppressive features

Abstract Breast cancer metastasis is known to be extensively promoted by immunosuppression. Here we describe a novel mechanism by which mesenchymal stem cell (MSC)-derived exosomes drive an immunosuppressive program within the breast tumor microenvironment. Initial q-PCR and immunophenotyping of hum...

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Bibliographic Details
Published inThe Journal of immunology (1950) Vol. 202; no. 1_Supplement; pp. 135 - 135.25
Main Authors BISWAS, SUBIR, Mandal, Gunjan, Chowdhury, Sougata Roy, Purohit, Suman, Payne, Kyle K., Galindo, Carmen Maria Anadon, Gupta, Arnab, Yu, Xiaoqing, Conejo-Garcia, Jose R., Bhattacharyya, Arindam
Format Journal Article
LanguageEnglish
Published 01.05.2019
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