Induced blood flow oscillations at 0.1 Hz protects oxygenation of severely ischemic tissue in humans

• Published in: Journal of applied physiology (1985) Vol. 137; no. 5; pp. 1243 - 1256
• Main Authors: Davis, K Austin, Bhuiyan, Nasrul A, McIntyre, Benjamin J, Dinh, Viet Q, Rickards, Caroline A
• Format: Journal Article
• Language: English
• Published: United States 01.11.2024
• Subjects: Adult; Arterial Pressure - physiology; Blood Flow Velocity - physiology; Brachial Artery - metabolism; Brachial Artery - physiology; Brachial Artery - physiopathology; Cerebrovascular Circulation - physiology; Female; Forearm - blood supply; Hemodynamics - physiology; Humans; Ischemia - metabolism; Ischemia - physiopathology; Male; Muscle, Skeletal - blood supply; Muscle, Skeletal - metabolism; Oxygen - metabolism; Oxygen Consumption - physiology; Regional Blood Flow - physiology; Young Adult; 0.1 Hz; tissue ischemia; tissue oxygenation; blood flow; hemodynamic oscillations

Generating 10-s (∼0.1 Hz) fluctuations or "oscillations" in arterial pressure and blood flow blunts reductions in cerebral tissue oxygenation in response to 15%-20% reductions in cerebral blood flow. To examine the effect of 0.1 Hz hemodynamic oscillations on tissue oxygenation during seve...