Association of intestinal exfoliome and Prevotellaceae with toxicity and clinical outcome during immune-checkpoint blockade

• Published in: Journal of clinical oncology Vol. 43; no. 16_suppl; p. 2664
• Main Authors: Vitali, Giacomo, Alves Costa Silva, Carolina, Oudabi, Dina, Ungolo, Cinzia, Arlunno, Bryan, Bonato, Adele, Belluomini, Lorenzo, Loriot, Yohann, Albiges, Laurence, Routy, Bertrand, Planchard, David, Besse, Benjamin, Zitvogel, Laurence
• Format: Journal Article
• Language: English
• Published: American Society of Clinical Oncology 01.06.2025

2664Background: Immune-related adverse events (irAEs) are autoimmune side effects related to ICI, varying in severity, onset and organ involvement that may be hard to differentiate from non-irAEs. Some reports have demonstrated that gut microbiota (GM) plays a role in modulating the risk of AEs. In...