Copy-number and targeted sequencing analyses to identify distinct prognostic groups: Implications for patient selection to targeted therapies amongst anti-endocrine therapy resistant early breast cancers

• Published in: Journal of clinical oncology Vol. 35; no. 15_suppl; p. 524
• Main Authors: Bayani, Jane, Kornaga, Elizabeth, Crozier, Cheryl, Jang, Gun Ho, Kalatskaya, Irina, Trinh, Quang M, Yao, Cindy Q, Livingstone, Julie, Hasenburg, Annette, Kieback, Dirk G, Markopoulos, Christos, Dirix, Luc, Boutros, Paul Christopher, Spears, Melanie, Stein, Lincoln D., Rea, Daniel, Bartlett, John
• Format: Journal Article
• Language: English
• Published: 20.05.2017

Abstract only 524 Background: Hormone receptor positive breast cancer is a therapeutic challenge. Despite optimal anti-endocrine therapies, most breast cancer deaths follow a diagnosis of early luminal cancer. To understand the impact of multiple aberrations in the context of current therapy, we ass...