miR‐1322 regulates Ch REBP expression via binding a 3′‐ UTR variant (rs1051943)

• Published in: Journal of cellular and molecular medicine Vol. 22; no. 11; pp. 5322 - 5332
• Main Authors: Zhang, Ying, Hu, Sen‐Lin, Hu, Dong, Jiang, Jian‐Gang, Cui, Guang‐Lin, Liu, Xing‐De, Wang, Dao Wen
• Format: Journal Article
• Language: English
• Published: Chichester John Wiley & Sons, Inc 01.11.2018
• Subjects: 3' Untranslated regions; Alleles; Binding sites; Cholesterol; Gene frequency; Genetic diversity; Glucose; Glucose metabolism; Lipid metabolism; Lipids; Minority & ethnic groups; Palmitic acid; Population genetics; Population studies; Transcription; Triglycerides

The carbohydrate response element‐binding protein (Ch REBP ), also referred to as MLXIPL , plays a crucial role in the regulation of glucose and lipid metabolism. Existing studies have shown an association between genetic variations of the Ch REBP gene and lipid levels, such as triglycerides and hig...