ROR1 as a Therapeutic Target In E2A-PBX1-Positive Acute Lymphoblastic Leukemia

• Published in: Blood Vol. 116; no. 21; p. 539
• Main Authors: Bicocca, Vincent, Chang, Bill H, Muschen, Markus, Druker, Brian J, Tyner, Jeffrey W
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 19.11.2010

Abstract 539 Aberrant tyrosine kinase activity is commonly implicated in the pathogenesis of leukemia and other cancers. Identification of these leukemogenic tyrosine kinases has proven invaluable for diagnostic and prognostic stratification of patients as well as for the development of novel strate...