Spatial Dynamics of T and B Cell Response Predicts Clinical Outcome of Resectable and Unresectable Hepatocellular Carcinoma

• Published in: Clinical cancer research
• Main Authors: Kurebayashi, Yutaka, Sugimoto, Katsutoshi, Tsujikawa, Hanako, Matsuda, Kosuke, Nomura, Rui, Ueno, Akihisa, Masugi, Yohei, Yamazaki, Ken, Effendi, Kathryn, Takeuchi, Hirohito, Itoi, Takao, Hasegawa, Yasushi, Abe, Yuta, Kitago, Minoru, Ojima, Hidenori, Sakamoto, Michiie
• Format: Journal Article
• Language: English
• Published: United States 17.10.2024

Immunotherapies have led to a paradigm shift in the treatment of hepatocellular carcinoma (HCC). Studies have revealed the single-cell catalogues of tumor-infiltrating immune cells and the trajectories of their differentiation. Nevertheless, the spatial distribution of these immune cells with distin...