Abstract B77: Vitamin D suppresses pancreatic cancer growth through inhibition of autocrine Wnt/β-catenin signaling

• Published in: Cancer research (Chicago, Ill.) Vol. 75; no. 13_Supplement; p. B77
• Main Authors: Arensman, Michael Dawson, Ostertag-Hill, Claire, Lay, Anna Rose, Dawson, David
• Format: Journal Article
• Language: English
• Published: 01.07.2015

Abstract Epidemiological studies indicate higher vitamin D levels are associated with a reduced risk for pancreatic ductal adenocarcinoma (PDAC) and other malignancies. Although vitamin D analogs inhibit the growth of some PDAC cell lines in vitro and in vivo, a clinical trial with an active metabol...