Long-term follow-up of facilitated cascade genetic testing for familial cancer syndromes: do at-risk relatives act on the information gained and what are the quality of life implications?

• Published in: Gynecologic oncology Vol. 162; pp. S199 - S200
• Main Authors: Badiner, Nora, Fowlkes, Rana, Nitecki, Roni, Rauh-Hain, Jose, Cornelius-Schecter, Anna, Kahn, Ryan, Chapman-Davis, Eloise, Tubito, Francesca, Christos, Paul, Sharaf, Ravi, Holcomb, Kevin, Lipkin, Steven, Frey, Melissa
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.08.2021

In a pilot study, we found that facilitated cascade genetic testing for cancer-associated pathogenic mutations with telephone counseling and mailed saliva kits resulted in testing of 58% of at-risk relatives (ARRs), significantly higher than prior reports. To ascertain the true value of cascade test...