911 Treatment and outcome of patients with extragonadal germ cell tumors

48 patients, 32 with abdominal and 16 with mediastinal extragonadal germ cell tumors were included in this study. 2 were women with mediastinal primaries. At presentation most patients had advanced disease. The median size of the tumors were 128 mm (abdominal) and 116 mm (mediastinal), respectively....

Full description

Saved in:
Bibliographic Details
Published inEuropean journal of cancer (1990) Vol. 31; p. S189
Main Authors Dueland, S., Stenwig, A.E., Heilo, A., Fosså, S.D.
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.11.1995
Online AccessGet full text

Cover

More Information
Summary:48 patients, 32 with abdominal and 16 with mediastinal extragonadal germ cell tumors were included in this study. 2 were women with mediastinal primaries. At presentation most patients had advanced disease. The median size of the tumors were 128 mm (abdominal) and 116 mm (mediastinal), respectively. Of the 48 patients, 14 had metastasis to liver, brain, and/or bone at time of diagnosis. Patients with metastasis to these organs had particularly poor survival. 7 patients died due to treatmentrelated toxicity. The median age of these seven patients were significantly higher than among the other patients. The 5-year survival of all 48 patients was 55%. 29 patients received CR after chemotherapy, determined by CT-scan and/or biopsy. 28 of these are still alive.
ISSN:0959-8049
1879-0852
DOI:10.1016/0959-8049(95)96160-F