Functional sequence variants of intergenic long non-coding RNA on Chromosome 17q21 are associated with asthma

• Published in: The European respiratory journal p. 2500847
• Main Authors: Liu, Kwei-Yan, Sie, Jia-Jyun, Gao, Yajing, Lo, Yen-Li, Wu, Chao-Chien, Wang, Chin-Chou, Sheu, Chau-Chyun, Lai, Ruay-Sheng, Leung, Sum-Yee, Lin, Chi-Cheng, Wei, Yu-Feng, Lin, Ching-Hsiung, Lin, Sheng-Hao, Hsu, Jeng-Yuan, Huang, Wei-Chang, Tseng, Chia-Cheng, Lai, Yung-Fa, Cheng, Meng-Hsuan, Chen, Huang-Chi, Yang, Chih-Jen, Hsu, Yuan-Ting, Su, Chian-Heng, Hsu, Shih-Chang, Chung, Wen-Yu, Hsieh, Ming-Tsuen, Chen, Li-Chen, Hung, Chih-Hsing, Lee, Chon-Lin, Huang, Ming-Shyan, Zhou, Yufeng, Fann, Cathy S. J., Huang, Shau-Ku
• Format: Journal Article
• Language: English
• Published: England 03.07.2025

The genetic and molecular basis of asthma remains unclear and its gene-environment interaction is still enigmatic. In the present study, we aimed to identify asthma-causing genetic variants and their interactions with the environment. We performed case-control genome-wide association studies on indi...