Stereotactic Radiotherapy vs. Whole Brain Radiation Therapy in EGFR Mutated NSCLC: Results and Reflections from the Prematurely Closed Phase III HYBRID Trial

• Published in: International journal of radiation oncology, biology, physics Vol. 120; no. 2; p. e294
• Main Authors: Zeng, M., Verma, V., Luo, X.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.10.2024

All known randomized trials of stereotactic radiotherapy (SRT) versus whole brain radiotherapy (WBRT) for brain metastases (BMs) comprise mixed histologies. The phase III HYBRID trial (NCT02882984) attempted to evaluate non-inferiority of SRT vs. WBRT specifically for EGFR-mutated non-small cell lun...