Total neoadjuvant therapy (TnT) with FOLFOX followed by short course radiation in locally advanced rectal cancer: A phase II study

• Published in: Journal of clinical oncology Vol. 42; no. 3_suppl; p. 122
• Main Authors: Gim, Gahyun, Baran, Andrea M., Wang, Wenjia, Zittel, Jason, Hezel, Aram F, Ramsdale, Erika E., Badri, Nabeel, McGreevy, Maria, Qiu, Haoming, Mulkerin, Daniel, Temple, Larissa K. F., Cellini, Christina, Fleming, Fergal J., Noel, Marcus Smith, Dunne, Richard Francis
• Format: Journal Article
• Language: English
• Published: American Society of Clinical Oncology 20.01.2024

122Background: Total neoadjuvant therapy (TnT) is a new standard-of-care for locally advanced rectal cancer (LARC). Few prospective studies have evaluated specifically the use of chemotherapy and short course radiation (SCRT) in obtaining a complete clinical response (cCR) and offering non-operative...