Pitch session 2Functional interation of endoplasmic reticulum aminopeptidase ERAP2 and the peptidome of the main MHC-I-associated inflammatory disorders

• Published in: Molecular immunology Vol. 150; p. 20
• Main Authors: Martin-Esteban, Adrián, Sanz-Bravo, Alejandro, Guasp, Pablo, Kuiper, Jonas, Garcia-Peyro, Marina, Barnea, Eilon, Admon, Arie, Lopez de Castro, Jose Antonio
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.10.2022

Several inflammatory diseases are strongly associated with Major Histocompatibility Complex class I (MHC-I) molecules: Among them birdshot chorioretinopathy (HLA-A*29:02) and ankylosing spondylitis (HLA-B*27) have the strongest association with about 100 and 90% of patients being A*29:02 and B*27 po...