Bile acid fitness determinants of a Bacteroides fragilis isolate from a human pouchitis patient

• Published in: bioRxiv
• Main Authors: Fiebig, Aretha, Schnizlein, Matthew K, Pena-Rivera, Selymar, Trigodet, Florian, Dubey, Abhishek Anil, Hennessy, Miette, Basu, Anindita, Pott, Sebastian, Dalal, Sushila, Rubin, David, Sogin, Mitchell L, Murat Eren, A, Chang, Eugene B, Crosson, Sean
• Format: Journal Article Paper
• Language: English
• Published: United States Cold Spring Harbor Laboratory 17.10.2023
• Edition: 1.2
• Subjects: Microbiology

comprises 1-5% of the gut microbiota in healthy humans but can expand to >50% of the population in ulcerative colitis (UC) patients experiencing inflammation. The mechanisms underlying such microbial blooms are poorly understood, but the gut of UC patients has physicochemical features that differ...