Partial Correlation Analysis Reveals Abnormal Retinotopically Organized Functional Connectivity of Visual Areas in Amblyopia

• Published in: bioRxiv
• Main Authors: Mendola, Janine, Lam, Jack, Rosenstein, Michelle, Lewis, Lindsay B, Amir Shmuel
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 21.12.2017; Cold Spring Harbor Laboratory
• Edition: 1.1
• Subjects: Acuity; Adaptation; Children; Correlation analysis; Functional magnetic resonance imaging; Neuroscience; Occipital lobe; Psychophysics; Structure-function relationships; Vision; Visual cortex; Visual field; Visual perception; regional; spontaneous activity; resting state functional connectivity; Functional MRI; partial correlation; intrinsic; strabismus, binocular vision, suppression; resting state functional magnetic resonance imaging

Amblyopia is a prevalent developmental visual disorder of childhood that typically persists in adults. Due to altered visual experience during critical periods of youth, the structure and function of adult visual cortex is abnormal. In addition to substantial deficits shown with task-based fMRI, pre...