The laboratory domestication of zebrafish: from diverse populations to inbred substrains

• Published in: bioRxiv
• Main Authors: Suurvaeli, Jaanus, Whiteley, Andrew R, Zheng, Yichen, Gharbi, Karim, Leptin, Maria, Wiehe, Thomas
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 18.07.2019; Cold Spring Harbor Laboratory
• Edition: 1.1
• Subjects: Danio rerio; DNA sequencing; Domestication; Gene conversion; Gene frequency; Genetic diversity; Genetics; Genomes; Heterozygosity; Inbreeding; Laboratories; Nucleotide sequence; Population genetics; Population studies; Zebrafish; Bangladesh; Nepal; genetic diversity; laboratory strains; RAD-seq; genetic differentiation; zebrafish; inbreeding; wild populations

The zebrafish (Danio rerio) is a model vertebrate widely used to study disease, development and other aspects of vertebrate biology. Most of the research is performed on laboratory strains, one of which has been fully sequenced in order to derive a reference genome. It is known that the laboratory s...