IL-11 produced by breast cancer cells augments osteoclastogenesis by sustaining the pool of osteoclast progenitor cells

Interleukin (IL)-11, a cytokine produced by breast cancer, has been implicated in breast cancer-induced osteolysis (bone destruction) but the mechanism(s) of action remain controversial. Some studies show that IL-11 is able to promote osteoclast formation independent of the receptor activator of NF-...

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Bibliographic Details
Published inBMC cancer Vol. 13; no. 1; p. 16
Main Authors McCoy, Erin M, Hong, Huixian, Pruitt, Hawley C, Feng, Xu
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 11.01.2013
BioMed Central
BMC
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