Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common - White, Nicholas J; Qiao, Li Guo; Qi, Gao; Luzzatto, Lucio (Malaria journal, 2012)
Keywords: Adult; Anemia, Hemolytic - chemically induced; Anemia, Hemolytic - enzymology; Anemia, Hemolytic - genetics; Animals; Anopheles; Anopheles - parasitology; Anopheles - pathogenicity; Antimalarials - administration & dosage; Antimalarials - adverse effects; Artemisinins - administration & dosage; Artemisinins - adverse effects; Biomedical and Life Sciences; Biomedicine; Complications and side effects; Disease transmission; Dosage and administration; Drug dosages; Drug Therapy, Combination; Entomology; Epidemiology; Erythrocytes; Female; Fever; Gametocytes; Glucosephosphate Dehydrogenase - genetics; Glucosephosphate Dehydrogenase Deficiency - complications; Glucosephosphate Dehydrogenase Deficiency - enzymology; Glucosephosphate Dehydrogenase Deficiency - genetics; Humans; Infectious Diseases; Insect Vectors - parasitology; Insect Vectors - pathogenicity; Malaria; Malaria, Falciparum - complications; Malaria, Falciparum - drug therapy; Malaria, Falciparum - transmission; Male; Microbiology; Mortality; Mosquitoes; Parasitemia - complications; Parasitemia - drug therapy; Parasitology; Physiological aspects; Plasmodium falciparum; Plasmodium falciparum - drug effects; Prevention; Primaquine; Primaquine - administration & dosage; Primaquine - adverse effects; Public Health; Review; Studies; Tropical Medicine; G6PD Activity; Malaria; G6PD Deficiency; Primaquine; Falciparum Malaria