Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common

In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin combination treatment (ACT) in acute falciparum malaria to block malaria transmission. Review of studies of transmission-blocking activity ba...

Full description

Saved in:
Bibliographic Details
Published inMalaria journal Vol. 11; no. 1; p. 418
Main Authors White, Nicholas J, Qiao, Li Guo, Qi, Gao, Luzzatto, Lucio
Format Journal Article
LanguageEnglish
Published London BioMed Central 14.12.2012
BioMed Central Ltd
BMC
Subjects
Online AccessGet full text
ISSN1475-2875
1475-2875
DOI10.1186/1475-2875-11-418

Cover

Abstract In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin combination treatment (ACT) in acute falciparum malaria to block malaria transmission. Review of studies of transmission-blocking activity based on the infectivity of patients or volunteers to anopheline mosquitoes, and of haemolytic toxicity in glucose 6-dehydrogenase (G6PD) deficient subjects, suggests that a lower primaquine dose (0.25 mg base/kg) would be safer and equally effective. This lower dose could be deployed together with ACTs without G6PD testing wherever use of a specific gametocytocide is indicated.
AbstractList In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin combination treatment (ACT) in acute falciparum malaria to block malaria transmission. Review of studies of transmission-blocking activity based on the infectivity of patients or volunteers to anopheline mosquitoes, and of haemolytic toxicity in glucose 6-dehydrogenase (G6PD) deficient subjects, suggests that a lower primaquine dose (0.25 mg base/kg) would be safer and equally effective. This lower dose could be deployed together with ACTs without G6PD testing wherever use of a specific gametocytocide is indicated.
Abstract In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin combination treatment (ACT) in acute falciparum malaria to block malaria transmission. Review of studies of transmission-blocking activity based on the infectivity of patients or volunteers to anopheline mosquitoes, and of haemolytic toxicity in glucose 6-dehydrogenase (G6PD) deficient subjects, suggests that a lower primaquine dose (0.25 mg base/kg) would be safer and equally effective. This lower dose could be deployed together with ACTs without G6PD testing wherever use of a specific gametocytocide is indicated.
Doc number: 418 Abstract: In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin combination treatment (ACT) in acute falciparum malaria to block malaria transmission. Review of studies of transmission-blocking activity based on the infectivity of patients or volunteers to anopheline mosquitoes, and of haemolytic toxicity in glucose 6-dehydrogenase (G6PD) deficient subjects, suggests that a lower primaquine dose (0.25 mg base/kg) would be safer and equally effective. This lower dose could be deployed together with ACTs without G6PD testing wherever use of a specific gametocytocide is indicated.
In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin combination treatment (ACT) in acute falciparum malaria to block malaria transmission. Review of studies of transmission-blocking activity based on the infectivity of patients or volunteers to anopheline mosquitoes, and of haemolytic toxicity in glucose 6-dehydrogenase (G6PD) deficient subjects, suggests that a lower primaquine dose (0.25 mg base/kg) would be safer and equally effective. This lower dose could be deployed together with ACTs without G6PD testing wherever use of a specific gametocytocide is indicated.In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin combination treatment (ACT) in acute falciparum malaria to block malaria transmission. Review of studies of transmission-blocking activity based on the infectivity of patients or volunteers to anopheline mosquitoes, and of haemolytic toxicity in glucose 6-dehydrogenase (G6PD) deficient subjects, suggests that a lower primaquine dose (0.25 mg base/kg) would be safer and equally effective. This lower dose could be deployed together with ACTs without G6PD testing wherever use of a specific gametocytocide is indicated.
ArticleNumber 418
Audience Academic
Author Qi, Gao
White, Nicholas J
Luzzatto, Lucio
Qiao, Li Guo
AuthorAffiliation 4 Istituto Toscano Tumori, Florence, Italy
2 Research Centre for Qinghao, Guangzhou University of Chinese Medicine, Guangzhou, China
3 Jiangsu Institute of Parasitic Diseases, Wuxi, China
1 Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
AuthorAffiliation_xml – name: 2 Research Centre for Qinghao, Guangzhou University of Chinese Medicine, Guangzhou, China
– name: 3 Jiangsu Institute of Parasitic Diseases, Wuxi, China
– name: 1 Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
– name: 4 Istituto Toscano Tumori, Florence, Italy
Author_xml – sequence: 1
  givenname: Nicholas J
  surname: White
  fullname: White, Nicholas J
  email: nickw@tropmedres.ac
  organization: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University
– sequence: 2
  givenname: Li Guo
  surname: Qiao
  fullname: Qiao, Li Guo
  organization: Research Centre for Qinghao, Guangzhou University of Chinese Medicine
– sequence: 3
  givenname: Gao
  surname: Qi
  fullname: Qi, Gao
  organization: Jiangsu Institute of Parasitic Diseases
– sequence: 4
  givenname: Lucio
  surname: Luzzatto
  fullname: Luzzatto, Lucio
  organization: Istituto Toscano Tumori
BackLink https://www.ncbi.nlm.nih.gov/pubmed/23237606$$D View this record in MEDLINE/PubMed
BookMark eNqNU8tu1DAUjVARfcCeFbLEhs0UO3YcZ4NUDVAqVaJCsLb8uJm6SuypnVDNT_DNODNlmKlahKIk1r3nnvs6Pi4OfPBQFK8JPiVE8PeE1dWsFPlDyIwR8aw42poOds6HxXFKNxiTWtTli-KwpCWtOeZHxa9vanDBqw5QGyKKYELfg7fOL5BCXbiDiGxIgEKLltH16nZ0HpBK2XvVqdQH68YetaozbqliPi5UD0Mwq_w6C8h5tAzLsVunSejuGiKgc371EVlonXHgzQq5hKa8wb8snmeqBK_u_yfFj8-fvs-_zC6_nl_Mzy5nuq7EMGNG5K6MwppXhFXMCtoYZqmGsjZ12dLGUmaNtjWtiKYMqGWaUG1bRYXKzZ8UFxteG9SNXDcWVzIoJ9eGEBdSxcGZDmRV4ZZXJVUMt4xqpq3SRAlCLSeNUSJzfdhwLUfdgzXgh6i6PdJ9j3fXchF-SloxLliTCeYbAu3CEwT7njwrOe1WTruVhMi8-szy7r6MGG5HSIPsXTLQdcpDGJMkpahww5io_wNaU17WTNAMffsAehPGmPUyoXjDCa5x8xe1yEKSzrch12kmUnlWUVbSpln3efoIKj8WemeysluX7XsBb3Ynu53IH_lmAN4ATAwpRWi3EILldEMeGxN_EGLcsBZnLsZ1_wokm8CUc_gFxJ1JPBXzG2hYJAY
CitedBy_id crossref_primary_10_1002_cpt_2512
crossref_primary_10_1016_S1473_3099_13_70268_8
crossref_primary_10_1016_S1473_3099_22_00658_2
crossref_primary_10_1136_bmjopen_2013_002759
crossref_primary_10_1371_journal_pone_0134593
crossref_primary_10_1186_s12936_023_04558_7
crossref_primary_10_1128_AAC_01948_15
crossref_primary_10_1016_j_parepi_2022_e00244
crossref_primary_10_1186_s12916_016_0701_8
crossref_primary_10_2139_ssrn_4111059
crossref_primary_10_69547_TSFJB_020203
crossref_primary_10_1371_journal_pntd_0006230
crossref_primary_10_1016_S1473_3099_15_00479_X
crossref_primary_10_1186_s12936_017_1864_2
crossref_primary_10_1016_j_actatropica_2014_03_011
crossref_primary_10_1111_bjh_12665
crossref_primary_10_1186_s13063_024_08428_8
crossref_primary_10_1002_cpt_1716
crossref_primary_10_1371_journal_pcbi_1003434
crossref_primary_10_1128_cmr_00109_24
crossref_primary_10_1371_journal_pone_0151898
crossref_primary_10_3389_fcimb_2022_820650
crossref_primary_10_1056_NEJMra1708111
crossref_primary_10_1097_INF_0000000000000306
crossref_primary_10_1186_1475_2875_12_112
crossref_primary_10_1186_s12936_016_1410_7
crossref_primary_10_1016_j_pt_2014_07_004
crossref_primary_10_1186_s12936_015_0821_1
crossref_primary_10_1016_S1473_3099_24_00741_2
crossref_primary_10_1371_journal_pone_0116143
crossref_primary_10_1016_j_bioorg_2019_103321
crossref_primary_10_1186_1475_2875_13_418
crossref_primary_10_1007_s13149_017_0556_z
crossref_primary_10_1093_infdis_jix237
crossref_primary_10_1371_journal_pone_0284751
crossref_primary_10_1586_14787210_2015_1031744
crossref_primary_10_1128_AAC_00139_13
crossref_primary_10_1186_s12936_021_03921_w
crossref_primary_10_2174_0113816128321468240828103439
crossref_primary_10_1124_dmd_114_061127
crossref_primary_10_1093_jac_dky297
crossref_primary_10_1186_s12881_017_0496_2
crossref_primary_10_1186_s41182_022_00408_5
crossref_primary_10_1111_1469_0691_12316
crossref_primary_10_1186_s41182_021_00339_7
crossref_primary_10_1136_bmjopen_2013_004664
crossref_primary_10_1371_journal_pbio_1002380
crossref_primary_10_1371_journal_pmed_1002745
crossref_primary_10_1186_1475_2875_12_332
crossref_primary_10_1186_s12936_016_1440_1
crossref_primary_10_1186_s12879_015_0887_y
crossref_primary_10_1093_infdis_jiaa498
crossref_primary_10_1186_1475_2875_13_483
crossref_primary_10_1186_s13063_015_0597_1
crossref_primary_10_1186_s12916_017_0990_6
crossref_primary_10_4236_aid_2018_82006
crossref_primary_10_1128_AAC_03942_14
crossref_primary_10_1186_s12936_016_1662_2
crossref_primary_10_1016_j_phytochem_2020_112336
crossref_primary_10_1128_AAC_00287_13
crossref_primary_10_1186_s12916_023_03105_0
crossref_primary_10_1186_s12936_016_1632_8
crossref_primary_10_1186_s12936_018_2390_6
crossref_primary_10_1128_aac_01481_21
crossref_primary_10_1186_s12936_024_04947_6
crossref_primary_10_1186_s12916_016_0581_y
crossref_primary_10_1186_s12936_016_1341_3
crossref_primary_10_1080_1061186X_2017_1291645
crossref_primary_10_1128_AAC_03704_14
crossref_primary_10_1002_14651858_CD008152_pub4
crossref_primary_10_1186_1475_2875_12_391
crossref_primary_10_4269_ajtmh_22_0375
crossref_primary_10_1002_14651858_CD008152_pub5
crossref_primary_10_1371_journal_pone_0125796
crossref_primary_10_1182_blood_2019000944
crossref_primary_10_1021_acs_molpharmaceut_1c00520
crossref_primary_10_1093_cid_ciu802
crossref_primary_10_1186_1475_2875_12_418
crossref_primary_10_1371_journal_pone_0168702
crossref_primary_10_1093_infdis_jiy014
crossref_primary_10_1093_trstmh_trz035
crossref_primary_10_1016_S1473_3099_18_30046_X
crossref_primary_10_1186_s13071_021_05034_4
crossref_primary_10_1016_j_hoc_2015_11_006
crossref_primary_10_1186_1475_2875_12_383
crossref_primary_10_1186_s12916_015_0441_1
crossref_primary_10_1186_s12916_022_02504_z
crossref_primary_10_1186_s12936_023_04801_1
crossref_primary_10_1038_s41598_019_55437_8
crossref_primary_10_3390_diagnostics10040229
crossref_primary_10_1186_s12936_019_2841_8
crossref_primary_10_1586_17512433_2014_948421
crossref_primary_10_1016_j_ebiom_2016_10_032
crossref_primary_10_1186_s12936_016_1399_y
crossref_primary_10_1186_s12936_020_03359_6
crossref_primary_10_3389_fcimb_2024_1330475
crossref_primary_10_1111_bcp_14474
crossref_primary_10_1016_j_ejmech_2018_01_062
crossref_primary_10_1517_14656566_2014_944499
crossref_primary_10_1186_s12936_016_1344_0
crossref_primary_10_1186_s12879_017_2378_9
crossref_primary_10_1186_s12936_022_04100_1
crossref_primary_10_1128_CMR_00011_19
crossref_primary_10_1186_s12936_015_0714_3
Cites_doi 10.1128/AAC.01472-05
10.1056/NEJMoa0808859
10.1128/CMR.00051-10
10.1016/S0140-6736(96)91488-9
10.1371/journal.pone.0001023
10.1182/blood.V25.1.92.92
10.1182/blood.V14.2.103.103
10.2307/4579280
10.4269/ajtmh.2011.11-0498
10.1371/journal.pmed.1001339
10.1046/j.1365-3156.2003.01169.x
10.1016/S0140-6736(10)61963-0
10.1111/j.1365-2125.1993.tb05685.x
10.1016/0035-9203(49)90051-6
10.1371/journal.pone.0001311
10.1001/jama.1962.03050180034008a
10.4269/ajtmh.1955.4.781
10.1016/j.actatropica.2005.04.014
10.1016/S0140-6736(08)60073-2
10.1128/AAC.48.4.1329-1334.2004
10.1016/j.pt.2008.07.009
10.1016/S0140-6736(00)96054-9
10.1186/1475-2875-7-125
10.1126/science.1063292
10.1016/S1658-3876(09)50025-8
10.1186/1475-2875-7-249
10.1016/S0140-6736(12)60484-X
10.1182/blood.V84.11.3613.bloodjournal84113613
10.1016/S1473-3099(10)70187-0
10.1182/blood-2012-03-416032
10.1128/AAC.01135-09
ContentType Journal Article
Copyright White et al.; licensee BioMed Central Ltd. 2012
COPYRIGHT 2012 BioMed Central Ltd.
2012 White et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright ©2012 White et al.; licensee BioMed Central Ltd. 2012 White et al.; licensee BioMed Central Ltd.
Copyright_xml – notice: White et al.; licensee BioMed Central Ltd. 2012
– notice: COPYRIGHT 2012 BioMed Central Ltd.
– notice: 2012 White et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
– notice: Copyright ©2012 White et al.; licensee BioMed Central Ltd. 2012 White et al.; licensee BioMed Central Ltd.
DBID C6C
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7SS
7U9
7X7
7XB
88E
8C1
8FI
8FJ
8FK
ABUWG
AEUYN
AFKRA
AZQEC
BENPR
C1K
CCPQU
DWQXO
F1W
FYUFA
GHDGH
H94
H95
H97
K9.
L.G
M0S
M1P
M7N
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
7X8
5PM
DOA
DOI 10.1186/1475-2875-11-418
DatabaseName Springer Nature OA Free Journals
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Entomology Abstracts (Full archive)
Virology and AIDS Abstracts
Health & Medical Collection (Proquest)
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Public Health Database
ProQuest Hospital Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest One Sustainability
ProQuest Central UK/Ireland
ProQuest Central Essentials
ProQuest Central
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Central
ASFA: Aquatic Sciences and Fisheries Abstracts
Health Research Premium Collection
Health Research Premium Collection (Alumni)
AIDS and Cancer Research Abstracts
Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources
Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality
ProQuest Health & Medical Complete (Alumni)
Aquatic Science & Fisheries Abstracts (ASFA) Professional
ProQuest Health & Medical Collection
Medical Database
Algology Mycology and Protozoology Abstracts (Microbiology C)
ProQuest Central Premium
ProQuest One Academic
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Publicly Available Content Database
Aquatic Science & Fisheries Abstracts (ASFA) Professional
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Central China
Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality
Environmental Sciences and Pollution Management
ProQuest Central
ProQuest One Sustainability
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Algology Mycology and Protozoology Abstracts (Microbiology C)
Health & Medical Research Collection
AIDS and Cancer Research Abstracts
Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest Public Health
Virology and AIDS Abstracts
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Hospital Collection (Alumni)
Entomology Abstracts
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ASFA: Aquatic Sciences and Fisheries Abstracts
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList




Publicly Available Content Database
Aquatic Science & Fisheries Abstracts (ASFA) Professional
MEDLINE
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: C6C
  name: Springer Nature OA Free Journals
  url: http://www.springeropen.com/
  sourceTypes: Publisher
– sequence: 2
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 3
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 4
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 5
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Public Health
EISSN 1475-2875
EndPage 418
ExternalDocumentID oai_doaj_org_article_550f6523a40f43b4bdab1a813d619ca8
PMC3546849
oai_biomedcentral_com_1475_2875_11_418
2866259591
A534239949
23237606
10_1186_1475_2875_11_418
Genre Journal Article
Review
GrantInformation_xml – fundername: Wellcome Trust
  grantid: 093956
– fundername: Wellcome Trust
  grantid: 089275
GroupedDBID ---
0R~
29M
2WC
4.4
53G
5VS
7X7
88E
8C1
8FI
8FJ
AAFWJ
AAJSJ
AASML
ABDBF
ABUWG
ACGFO
ACGFS
ACIHN
ACMJI
ACPRK
ACUHS
ADBBV
ADRAZ
ADUKV
AEAQA
AENEX
AEUYN
AFKRA
AFPKN
AHBYD
AHMBA
AHSBF
AHYZX
ALMA_UNASSIGNED_HOLDINGS
AMKLP
AMTXH
AOIJS
BAPOH
BAWUL
BCNDV
BENPR
BFQNJ
BMC
BPHCQ
BVXVI
C6C
CCPQU
CS3
DIK
DU5
E3Z
EAD
EAP
EAS
EBD
EBLON
EBS
ECGQY
EJD
EMB
EMK
EMOBN
ESX
F5P
FYUFA
GROUPED_DOAJ
GX1
HMCUK
HYE
IAO
IHR
INH
INR
IPNFZ
ITC
KQ8
M1P
M48
M~E
O5R
O5S
OK1
OVT
P2P
PGMZT
PHGZM
PHGZT
PIMPY
PJZUB
PPXIY
PQQKQ
PROAC
PSQYO
PUEGO
RBZ
RIG
RNS
ROL
RPM
RSV
SBL
SOJ
SV3
TR2
TUS
U2A
UKHRP
W2D
WOQ
WOW
XSB
AAYXX
ALIPV
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
PMFND
2VQ
3V.
7SS
7U9
7XB
8FK
AZQEC
C1K
DWQXO
F1W
H94
H95
H97
K9.
L.G
M7N
PKEHL
PQEST
PQUKI
PRINS
7X8
-A0
ABVAZ
ACRMQ
ADINQ
AFGXO
AFNRJ
C24
FRP
5PM
ID FETCH-LOGICAL-b758t-4c8875ca0b651454d839c4d3be27c72f39d34dcbd7351b34e3d4b13bdfa38a323
IEDL.DBID M48
ISSN 1475-2875
IngestDate Wed Aug 27 01:30:30 EDT 2025
Thu Aug 21 14:34:39 EDT 2025
Wed May 22 07:14:53 EDT 2024
Fri Sep 05 08:26:23 EDT 2025
Fri Sep 05 08:54:10 EDT 2025
Fri Jul 25 07:14:40 EDT 2025
Tue Jun 17 22:05:40 EDT 2025
Tue Jun 10 21:03:18 EDT 2025
Mon Jul 21 06:00:51 EDT 2025
Thu Apr 24 23:00:13 EDT 2025
Tue Jul 01 02:39:34 EDT 2025
Sat Sep 06 07:24:50 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords G6PD Activity
Malaria
G6PD Deficiency
Primaquine
Falciparum Malaria
Language English
License http://creativecommons.org/licenses/by/2.0
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-b758t-4c8875ca0b651454d839c4d3be27c72f39d34dcbd7351b34e3d4b13bdfa38a323
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
OpenAccessLink https://link.springer.com/10.1186/1475-2875-11-418
PMID 23237606
PQID 1269610709
PQPubID 42600
PageCount 1
ParticipantIDs doaj_primary_oai_doaj_org_article_550f6523a40f43b4bdab1a813d619ca8
pubmedcentral_primary_oai_pubmedcentral_nih_gov_3546849
biomedcentral_primary_oai_biomedcentral_com_1475_2875_11_418
proquest_miscellaneous_1285094487
proquest_miscellaneous_1273627483
proquest_journals_1269610709
gale_infotracmisc_A534239949
gale_infotracacademiconefile_A534239949
pubmed_primary_23237606
crossref_primary_10_1186_1475_2875_11_418
crossref_citationtrail_10_1186_1475_2875_11_418
springer_journals_10_1186_1475_2875_11_418
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2012-12-14
PublicationDateYYYYMMDD 2012-12-14
PublicationDate_xml – month: 12
  year: 2012
  text: 2012-12-14
  day: 14
PublicationDecade 2010
PublicationPlace London
PublicationPlace_xml – name: London
– name: England
PublicationTitle Malaria journal
PublicationTitleAbbrev Malar J
PublicationTitleAlternate Malar J
PublicationYear 2012
Publisher BioMed Central
BioMed Central Ltd
BMC
Publisher_xml – name: BioMed Central
– name: BioMed Central Ltd
– name: BMC
References NJ White (2605_CR15) 2012
JH Edgecomb (2605_CR26) 1950; 9
K Chotivanich (2605_CR10) 2006; 50
SA Al-Sweedan (2605_CR43) 2009; 2
RE Howes (2605_CR3) 2012; 9
F Smithuis (2605_CR13) 2010; 10
K Stepniewska (2605_CR29) 2008; 7
S Shekalaghe (2605_CR7) 2007; 2
2605_CR39
L Luzzatto (2605_CR1) 2008
AM Dondorp (2605_CR49) 2009; 361
HY Myint (2605_CR31) 2011; 85
RN Price (2605_CR6) 1996; 347
SA Shekalaghe (2605_CR48) 2010; 54
GJ Brewer (2605_CR37) 1967; 36
GM Jeffery (2605_CR16) 1955; 4
PH Manson-Bahr (2605_CR24) 1928; 214
P Mühlens (2605_CR19) 1927; 31
E Beutler (2605_CR33) 1994; 84
GQ Li (2605_CR28) 2003–2004
MA Barber (2605_CR21) 1927
G Edwards (2605_CR38) 1993; 35
JN George (2605_CR46) 1967; 70
IM Pannacciulli (2605_CR45) 1965; 25
NJ White (2605_CR53) 2010; 376
2605_CR5
R Rosenberg (2605_CR30) 2008; 24
E Beutler (2605_CR32) 1959; 14
A Pamba (2605_CR42) 2012; 120
S Pukrittayakamee (2605_CR8) 2004; 48
AS Alving (2605_CR35) 1960; 22
AP Phyo (2605_CR50) 2012; 379
2605_CR51
KI Barnes (2605_CR17) 2005; 94
CJ Drakeley (2605_CR9) 2004; 9
LC Okell (2605_CR12) 2008; 7
MD Cappellini (2605_CR2) 2008; 371
T Bousema (2605_CR14) 2011; 24
F Jerace (2605_CR23) 1933; 12
MJ MacKerras (2605_CR25) 1949; 42
B El-Sayed (2605_CR11) 2007; 2
AV Kondrashin (2605_CR41) 2010; 4
World Health Organization (2605_CR4) 2010
W Roehl (2605_CR20) 1927; 31
DF Clyde (2605_CR40) 1962; 27
L Luzzatto (2605_CR47) 2001; 293
PM Graves (2605_CR52) 2012
P Mühlens (2605_CR18) 1926; 30
DF Clyde (2605_CR34) 1981; 59
PA Reeve (2605_CR44) 1992; 95
MD Young (2605_CR27) 1959; 13
RW Kellermeyer (2605_CR36) 1962; 180
MA Barber (2605_CR22) 1929; 44
15047537 - Antimicrob Agents Chemother. 2004 Apr;48(4):1329-34
7949118 - Blood. 1994 Dec 1;84(11):3613-36
21168039 - Lancet. 2010 Dec 18;376(9758):2051-2
14021798 - Bull World Health Organ. 1962;27:203-12
11463901 - Science. 2001 Jul 20;293(5529):442-3
15878154 - Acta Trop. 2005 Jun;94(3):230-40
13793053 - Bull World Health Organ. 1960;22:621-31
20118060 - Hematol Oncol Stem Cell Ther. 2009;2(2):354-7
8642959 - Lancet. 1996 Jun 15;347(9016):1654-8
16723547 - Antimicrob Agents Chemother. 2006 Jun;50(6):1927-30
21400709 - Med Parazitol (Mosk). 2010 Oct-Dec;(4):24-8
17925871 - PLoS One. 2007;2(10):e1023
18177777 - Lancet. 2008 Jan 5;371(9606):64-74
19055751 - Malar J. 2008;7:249
6976846 - Bull World Health Organ. 1981;59(3):391-5
13259002 - Am J Trop Med Hyg. 1955 Sep;4(5):781-9
19641202 - N Engl J Med. 2009 Jul 30;361(5):455-67
20194698 - Antimicrob Agents Chemother. 2010 May;54(5):1762-8
22144436 - Am J Trop Med Hyg. 2011 Dec;85(6):1010-4
22484134 - Lancet. 2012 May 26;379(9830):1960-6
14255977 - Blood. 1965 Jan;25:92-5
22993389 - Blood. 2012 Nov 15;120(20):4123-33
23152723 - PLoS Med. 2012;9(11):e1001339
20832366 - Lancet Infect Dis. 2010 Oct;10(10):673-81
18805735 - Trends Parasitol. 2008 Nov;24(11):487-91
23182932 - Lancet Infect Dis. 2013 Feb;13(2):175-81
18074034 - PLoS One. 2007;2(12):e1311
8443039 - Br J Clin Pharmacol. 1993 Feb;35(2):193-8
13618370 - Blood. 1959 Feb;14(2):103-39
21482730 - Clin Microbiol Rev. 2011 Apr;24(2):377-410
18613962 - Malar J. 2008;7:125
14728607 - Trop Med Int Health. 2004 Jan;9(1):53-61
4864652 - Bull World Health Organ. 1967;36(2):303-8
6027097 - J Lab Clin Med. 1967 Jul;70(1):80-93
18118367 - Trans R Soc Trop Med Hyg. 1949 Mar;42(5):455-63
22972117 - Cochrane Database Syst Rev. 2012;9:CD008152
1404560 - J Trop Med Hyg. 1992 Oct;95(5):349-51
14804087 - J Natl Malar Soc. 1950 Dec;9(4):285-92
14454972 - JAMA. 1962 May 5;180:388-94
References_xml – volume: 50
  start-page: 1927
  year: 2006
  ident: 2605_CR10
  publication-title: Antimicrob Agents Chemother
  doi: 10.1128/AAC.01472-05
– volume: 361
  start-page: 455
  year: 2009
  ident: 2605_CR49
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa0808859
– volume: 4
  start-page: 4
  year: 2010
  ident: 2605_CR41
  publication-title: Med Parazitol (Mosk)
– volume: 24
  start-page: 377
  year: 2011
  ident: 2605_CR14
  publication-title: Clin Microbiol Rev
  doi: 10.1128/CMR.00051-10
– volume: 13
  start-page: 69
  year: 1959
  ident: 2605_CR27
  publication-title: Ind J Malariol
– volume: 30
  start-page: 25
  year: 1926
  ident: 2605_CR18
  publication-title: Arch Schiffs Tropenhyg
– volume-title: Cochrane Database Syst Rev
  year: 2012
  ident: 2605_CR52
– volume: 347
  start-page: 1654
  year: 1996
  ident: 2605_CR6
  publication-title: Lancet
  doi: 10.1016/S0140-6736(96)91488-9
– volume: 2
  start-page: e1023
  year: 2007
  ident: 2605_CR7
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0001023
– volume: 25
  start-page: 92
  year: 1965
  ident: 2605_CR45
  publication-title: Blood
  doi: 10.1182/blood.V25.1.92.92
– volume: 14
  start-page: 103
  year: 1959
  ident: 2605_CR32
  publication-title: Blood
  doi: 10.1182/blood.V14.2.103.103
– volume-title: Guidelines for the Treatment of Malaria
  year: 2010
  ident: 2605_CR4
– volume: 44
  start-page: 1409
  year: 1929
  ident: 2605_CR22
  publication-title: Pub Hlth Rep United Fruit Co
  doi: 10.2307/4579280
– volume: 85
  start-page: 1010
  year: 2011
  ident: 2605_CR31
  publication-title: AmJTrop Med Hyg
  doi: 10.4269/ajtmh.2011.11-0498
– volume: 9
  start-page: e1001339
  year: 2012
  ident: 2605_CR3
  publication-title: PLoS Med
  doi: 10.1371/journal.pmed.1001339
– volume-title: Studies conducted in Xuan Loc Hospital, Dong Nai Province
  year: 2003–2004
  ident: 2605_CR28
– volume: 27
  start-page: 203
  year: 1962
  ident: 2605_CR40
  publication-title: Bull World Health Organ
– volume: 9
  start-page: 53
  year: 2004
  ident: 2605_CR9
  publication-title: Trop Med Int Health
  doi: 10.1046/j.1365-3156.2003.01169.x
– volume: 376
  start-page: 2051
  year: 2010
  ident: 2605_CR53
  publication-title: Lancet
  doi: 10.1016/S0140-6736(10)61963-0
– ident: 2605_CR5
– volume: 9
  start-page: 285
  year: 1950
  ident: 2605_CR26
  publication-title: J Natl Malar Soc
– volume: 35
  start-page: 193
  year: 1993
  ident: 2605_CR38
  publication-title: Br J Clin Pharmacol
  doi: 10.1111/j.1365-2125.1993.tb05685.x
– volume: 42
  start-page: 455
  year: 1949
  ident: 2605_CR25
  publication-title: Trans R Soc Trop Med Hyg
  doi: 10.1016/0035-9203(49)90051-6
– start-page: 883
  volume-title: Nathan & Oski's Hematology of Infancy and Chilhood
  year: 2008
  ident: 2605_CR1
– ident: 2605_CR39
– volume: 2
  start-page: 1311
  year: 2007
  ident: 2605_CR11
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0001311
– start-page: 60
  volume-title: 16thAnn Rept Med Dept United Fruit Co
  year: 1927
  ident: 2605_CR21
– volume-title: Lancet Infect Dis
  year: 2012
  ident: 2605_CR15
– volume: 180
  start-page: 388
  year: 1962
  ident: 2605_CR36
  publication-title: JAMA
  doi: 10.1001/jama.1962.03050180034008a
– volume: 4
  start-page: 781
  year: 1955
  ident: 2605_CR16
  publication-title: Am J Trop Med Hyg
  doi: 10.4269/ajtmh.1955.4.781
– volume: 94
  start-page: 230
  year: 2005
  ident: 2605_CR17
  publication-title: Acta Trop
  doi: 10.1016/j.actatropica.2005.04.014
– volume: 22
  start-page: 621
  year: 1960
  ident: 2605_CR35
  publication-title: Bull World Health Organ
– volume: 371
  start-page: 64
  year: 2008
  ident: 2605_CR2
  publication-title: Lancet
  doi: 10.1016/S0140-6736(08)60073-2
– volume: 48
  start-page: 1329
  year: 2004
  ident: 2605_CR8
  publication-title: Antimicrob Agents Chemother
  doi: 10.1128/AAC.48.4.1329-1334.2004
– volume: 36
  start-page: 303
  year: 1967
  ident: 2605_CR37
  publication-title: Bull World Health Organ
– volume: 24
  start-page: 487
  year: 2008
  ident: 2605_CR30
  publication-title: Trends Parasitol
  doi: 10.1016/j.pt.2008.07.009
– volume: 214
  start-page: 25
  year: 1928
  ident: 2605_CR24
  publication-title: Lancet
  doi: 10.1016/S0140-6736(00)96054-9
– volume: 7
  start-page: e125
  year: 2008
  ident: 2605_CR12
  publication-title: Malar J
  doi: 10.1186/1475-2875-7-125
– volume: 293
  start-page: 442
  year: 2001
  ident: 2605_CR47
  publication-title: Science
  doi: 10.1126/science.1063292
– volume: 59
  start-page: 391
  year: 1981
  ident: 2605_CR34
  publication-title: Bull World Health Organ
– volume: 31
  start-page: 7
  year: 1927
  ident: 2605_CR19
  publication-title: Arch Schiffs TropenHyg
– volume: 2
  start-page: 354
  year: 2009
  ident: 2605_CR43
  publication-title: Hematol Oncol Stem Cell Ther
  doi: 10.1016/S1658-3876(09)50025-8
– volume: 7
  start-page: e249
  year: 2008
  ident: 2605_CR29
  publication-title: Malar J
  doi: 10.1186/1475-2875-7-249
– volume: 379
  start-page: 1960
  year: 2012
  ident: 2605_CR50
  publication-title: Lancet
  doi: 10.1016/S0140-6736(12)60484-X
– volume: 84
  start-page: 3613
  year: 1994
  ident: 2605_CR33
  publication-title: Blood
  doi: 10.1182/blood.V84.11.3613.bloodjournal84113613
– ident: 2605_CR51
– volume: 10
  start-page: 673
  year: 2010
  ident: 2605_CR13
  publication-title: Lancet Infect Dis
  doi: 10.1016/S1473-3099(10)70187-0
– volume: 31
  start-page: 48
  year: 1927
  ident: 2605_CR20
  publication-title: Arch Schiffs TropenHyg
– volume: 120
  start-page: 4123
  year: 2012
  ident: 2605_CR42
  publication-title: Blood
  doi: 10.1182/blood-2012-03-416032
– volume: 70
  start-page: 80
  year: 1967
  ident: 2605_CR46
  publication-title: J Lab Clin Med
– volume: 95
  start-page: 349
  year: 1992
  ident: 2605_CR44
  publication-title: J Trop Med Hyg
– volume: 54
  start-page: 1762
  year: 2010
  ident: 2605_CR48
  publication-title: Antimicrob Agents Chemother
  doi: 10.1128/AAC.01135-09
– volume: 12
  start-page: 457
  year: 1933
  ident: 2605_CR23
  publication-title: Riv Malariol
– reference: 22972117 - Cochrane Database Syst Rev. 2012;9:CD008152
– reference: 14728607 - Trop Med Int Health. 2004 Jan;9(1):53-61
– reference: 19641202 - N Engl J Med. 2009 Jul 30;361(5):455-67
– reference: 20832366 - Lancet Infect Dis. 2010 Oct;10(10):673-81
– reference: 14255977 - Blood. 1965 Jan;25:92-5
– reference: 14021798 - Bull World Health Organ. 1962;27:203-12
– reference: 23182932 - Lancet Infect Dis. 2013 Feb;13(2):175-81
– reference: 18613962 - Malar J. 2008;7:125
– reference: 8642959 - Lancet. 1996 Jun 15;347(9016):1654-8
– reference: 17925871 - PLoS One. 2007;2(10):e1023
– reference: 22993389 - Blood. 2012 Nov 15;120(20):4123-33
– reference: 20118060 - Hematol Oncol Stem Cell Ther. 2009;2(2):354-7
– reference: 14804087 - J Natl Malar Soc. 1950 Dec;9(4):285-92
– reference: 6027097 - J Lab Clin Med. 1967 Jul;70(1):80-93
– reference: 8443039 - Br J Clin Pharmacol. 1993 Feb;35(2):193-8
– reference: 21482730 - Clin Microbiol Rev. 2011 Apr;24(2):377-410
– reference: 13259002 - Am J Trop Med Hyg. 1955 Sep;4(5):781-9
– reference: 19055751 - Malar J. 2008;7:249
– reference: 22484134 - Lancet. 2012 May 26;379(9830):1960-6
– reference: 11463901 - Science. 2001 Jul 20;293(5529):442-3
– reference: 13618370 - Blood. 1959 Feb;14(2):103-39
– reference: 21400709 - Med Parazitol (Mosk). 2010 Oct-Dec;(4):24-8
– reference: 1404560 - J Trop Med Hyg. 1992 Oct;95(5):349-51
– reference: 14454972 - JAMA. 1962 May 5;180:388-94
– reference: 13793053 - Bull World Health Organ. 1960;22:621-31
– reference: 18177777 - Lancet. 2008 Jan 5;371(9606):64-74
– reference: 18805735 - Trends Parasitol. 2008 Nov;24(11):487-91
– reference: 22144436 - Am J Trop Med Hyg. 2011 Dec;85(6):1010-4
– reference: 7949118 - Blood. 1994 Dec 1;84(11):3613-36
– reference: 23152723 - PLoS Med. 2012;9(11):e1001339
– reference: 21168039 - Lancet. 2010 Dec 18;376(9758):2051-2
– reference: 16723547 - Antimicrob Agents Chemother. 2006 Jun;50(6):1927-30
– reference: 20194698 - Antimicrob Agents Chemother. 2010 May;54(5):1762-8
– reference: 15878154 - Acta Trop. 2005 Jun;94(3):230-40
– reference: 18118367 - Trans R Soc Trop Med Hyg. 1949 Mar;42(5):455-63
– reference: 6976846 - Bull World Health Organ. 1981;59(3):391-5
– reference: 4864652 - Bull World Health Organ. 1967;36(2):303-8
– reference: 18074034 - PLoS One. 2007;2(12):e1311
– reference: 15047537 - Antimicrob Agents Chemother. 2004 Apr;48(4):1329-34
SSID ssj0017872
Score 2.3782442
SecondaryResourceType review_article
Snippet In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to artemisinin...
Doc number: 418 Abstract: In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult...
Abstract In areas of low malaria transmission, it is currently recommended that a single dose of primaquine (0.75 mg base/kg; 45 mg adult dose) be added to...
SourceID doaj
pubmedcentral
biomedcentral
proquest
gale
pubmed
crossref
springer
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 418
SubjectTerms Adult
Anemia, Hemolytic - chemically induced
Anemia, Hemolytic - enzymology
Anemia, Hemolytic - genetics
Animals
Anopheles
Anopheles - parasitology
Anopheles - pathogenicity
Antimalarials - administration & dosage
Antimalarials - adverse effects
Artemisinins - administration & dosage
Artemisinins - adverse effects
Biomedical and Life Sciences
Biomedicine
Complications and side effects
Disease transmission
Dosage and administration
Drug dosages
Drug Therapy, Combination
Entomology
Epidemiology
Erythrocytes
Female
Fever
Gametocytes
Glucosephosphate Dehydrogenase - genetics
Glucosephosphate Dehydrogenase Deficiency - complications
Glucosephosphate Dehydrogenase Deficiency - enzymology
Glucosephosphate Dehydrogenase Deficiency - genetics
Humans
Infectious Diseases
Insect Vectors - parasitology
Insect Vectors - pathogenicity
Malaria
Malaria, Falciparum - complications
Malaria, Falciparum - drug therapy
Malaria, Falciparum - transmission
Male
Microbiology
Mortality
Mosquitoes
Parasitemia - complications
Parasitemia - drug therapy
Parasitology
Physiological aspects
Plasmodium falciparum
Plasmodium falciparum - drug effects
Prevention
Primaquine
Primaquine - administration & dosage
Primaquine - adverse effects
Public Health
Review
Studies
Tropical Medicine
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1ti9QwEA5ynwQR362eRwRBFMq2m_QN_HKenoegHOLBfQt51cK2Xa-7iH_C3-xM-sLm9PSLLAtLJ92mmenkmSbzDCHPIIx1UkoeI1qOOVMmrqyr4kqxQsOnSgwmOH_4mJ-c8ffn2flOqS_cEzbQAw8DtwAE7XKIliRPHPwVV0aqVJYpMwD9tfRpvkmVTMHUuH4AZujXOXmRxRATZNMCZZkv5mOYUcax2EeQ6b4KJijP4_-7t96Zri5vpby0nuqnqeNb5OaIL-nhcF-3yTXb3iE3hpdzdMg5ukt-fhpfAVoKmJViUNw01ue3UElXWDiNmq63tHN0jXQU37YARqnsQXoKcLvpTL1tqJMr3JF9AT-_yMZuOv0DvrWxtG7peq4M1tPvYBiWvstP31BjkbIC8z1p3VO8btfeI2fHbz8fncRjYYZYQXixibkG15Rpmagc8FbGDaAszQ1TdgnqXTpWGcaNVqZgWaoYt8xwlYIdOMlKyZbsPtlru9Y-JBQAqnOlsQB8DNc2kzkiikQZDXEpKDEirwLtiPVAwiGQFjuUQJcFKlegciGyEaDciCwmZQo9kp5j7Y2V8MFPmf_hjBfzGdO1rm77Gu0j6JM_AAYsRgMW_zLgiDxH6xLoUKBrWo55ETA-SM0lDjNP0ljxKiL7QUtwBDoUT_YpRkfUi3SZV4CQiwTET2cxnomb61rbbbFNwbAEU8n-1qZEqkUIbyPyYDD5-bYBlOPWqjwiRfAwBOMSStr6q6cyZxnPS-z6y-mx2en6FaP-6H-M-mNyHaCvr-uT8n2yt7nY2icALzfqwHuSX672dbY
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: Public Health Database
  dbid: 8C1
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3ta9QwGA86vwgivludEkEQhXJtk6YtCDKncwjKEAf7FvLWWbi2t-sd4j_h3-zztGldpxvHwXFJ2zTPS35P8rwQ8hLM2FIpxUNEyyFn2oaFK4uw0Cwz8CkiiwHOX76Kw2P--SQ98RtunXerHHVir6hta3CPfBEnooClPouKd6uzEKtG4emqL6FxndyIQQejYOb7k4tHDMyYjEeTuVjEPEtDsBBSjCXjWOZjFuO-nC1NfQb_f_X0uYXqohPlhZPUfoE6uENue2RJ9wZWuEuuueYeuTVsy9Eh2ug--f3Nb_45CmiVojlc166PbKGKLrFkGrVt52hb0hUmojjbAgylqoPWIwDadWurbU1LtURf7DX8PFW127TmF3wr62jV0NVUE6yjP4ElHP0kjj5Q6zBZBUZ60qqj-Ny2eUCODz5-3z8MfUmGUINhsQm5AaWUGhVpAUgr5RbwleGWaZcAYZOSFZZxa7TNWBprxh2zXMfAAaViuWIJe0h2mrZxjwkFaFqWuXUAeSw3LlUCsUSkrQEqA-EC8nZGHbka0m9ITIg9b4EhSySuROKCTSOBuAFZjMSUxqc7x6obS9mbPbn4zxWvpyvGZ13e9z3yx2xM_R_t-lR6mZdg_JUCDH3FoxKkgGurdKzymFmwWo2Cm7xC7pKoSmBoRvmICJgfTMol99I-PWPBi4DsznqCCjDz5pE_pVdBnfwrMAF5MTXjlehW17h2i30yhsWXcnZVnxyTLIJhG5BHA8tPrw1wHJ2qRECymTDM5mXe0lQ_-iTmLOUix6G_GcXm3NAvmfUnV7_nU3IT4Gxfqyfmu2Rns966ZwAZN_p5rxf-AFC6ax4
  priority: 102
  providerName: ProQuest
– databaseName: SpringerLink Journals (ICM)
  dbid: U2A
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3ri9QwEA_n-UUQ8W3PUyIIolBu26Qv8Mv6OA9BOcSF-xbyPAvbdt3ucvhP-Dc7kz64rneCLIVlJ9mmmUd-02RmCHkJbqyTUvIQ0XLImTJhYV0RFoplGj7FzGCA85ev6cmCfz5LzvZIPMTC-NPuw5akt9RerfP0KOJZEgK-TzASjEf5DXIzAc8dlXERz8edAxDAeNiOvKLXTlz7crIc-az9f9vmS4vT7sHJnd1Tvygd3yV3ejRJ5x3775E9W98nt7tXcbSLMHpAfn_rX_hZCgiVogtcVdZHs1BJl1gmjZqmtbRxdIXJJ35uAXpS2QL1FMB11ZhyW1Enl3j-eg1fz2VlN43-BVdpLC1ruhrrgLX0AsTA0k_p6QdqLCaowOhOWrYU79vUD8ni-OP39ydhX4YhVOBMbEKuwRAlWs5UCugq4QYwleaGKRsDM2PHCsO40cpkLIkU45YZriLgupMslyxmj8h-3dT2CaEAR53LjQWYY7i2iUwRP8yU0eCFAuMC8nbCHbHqUm4ITII9pcCQBTJXIHPBjxHA3IAcDcwUuk9xjpU2lsK7Onl6RY_XY4_hXte3fYfyMRmT_6FZn4tezwU4fC4F517ymQPJ58pIFck8YgY8VS3hT16hdAk0HzA0LfsoCJgfTMQl5olPyVjwIiCHk5ag9npKHuRT9GanFVGcFoCHsxmQX4xk7IlH6WrbbLFNxrDgUs7-1SbHxIrgzAbkcSfy42MDBMeDVGlAsokyTOZlSqnLHz5xOUt4muPQ3wxqc2no18z6wf80fkpuAaD11Xoifkj2N-utfQagcaOeeyvxBzRSZx4
  priority: 102
  providerName: Springer Nature
Title Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common
URI https://link.springer.com/article/10.1186/1475-2875-11-418
https://www.ncbi.nlm.nih.gov/pubmed/23237606
https://www.proquest.com/docview/1269610709
https://www.proquest.com/docview/1273627483
https://www.proquest.com/docview/1285094487
http://dx.doi.org/10.1186/1475-2875-11-418
https://pubmed.ncbi.nlm.nih.gov/PMC3546849
https://doaj.org/article/550f6523a40f43b4bdab1a813d619ca8
Volume 11
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1ta9swEBZr-2Uwxt6XrQsaDMYGXmNLlm3YGGnWrgxaQlkg34Te3AUSO80LW__EfvPuFDuts3SMEJPkJFvR3UnPSbo7Qt6AGZsrpXiAaDngTNsgc3kWZJolBl5Zx6KD8-mZOBnwb8N4eO0eXXXgfKtph_mkBrPxh1-XV59B4T95hU_FQciTOADkH6OPGA_THbIH85JAU-yUX-8pgGj6vc-6dL1pueUOG97v48ak5WP7_z2C35jCNo9Xbuyx-qnr-AG5X2FO2l0JyUNyxxWPyL3Vgh1d-SE9Jr_Pq2VBRwHHUjSUJxPnfV6oomNMpkZtOXe0zOkUQ1RcLgGgUjUHah8g-KS0o-WE5mqMp7Rn8PFCTdyiNFfwHllHRwWdrrOFzelPEBZHv4r-F2odhrFAH1A6mlN8blk8IYPjo--9k6BK1hBoMDkWATcwXMVGdbQADBZzC8jLcMu0i4DlUc4yy7g12iYsDjXjjlmuQ5CNXLFUsYg9JbtFWbjnhAJozfPUOgBDlhsXK4Eoo6OtAVsVmNgiHxvckdNVYA6JobKbFGiyROZKZC5YOxKY2yIHNTOlqQKhYz6OsfQGUSq21Hi3rlE_6_ayhygfjTb5H8rZhaxGAwlmYS7iiCneyUE_uLZKhyoNmQV71ii4yVuULoliD00zqvKVgP7BcF2yG_vAjRnPWmS_URIGB9Mk1_Ipa92SYSQyQM1JB8iv12SsiQfuClcusUzCMC1Tyv5VJsXwi2Dytsizlciv_zYAdTxuJVokaShDo1-alGL0w4c3ZzEXKTb9fa02N5p-S6-_-O8Oe0nuAub1CX1Cvk92F7OlewW4cqHbZCcZJnBNe2Gb7B0enfXP4VtP9Np-pabthxO4DqLuH5cvego
linkProvider Scholars Portal
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3raxQxEA-lflAQ8e1q1QiKKCx3u8m-QJFqrVf7oEgL9y3Na-vB7e719o7Sf8I_xb_RmX3ZrbbfynFwXJLdSWYy-U2SmSHkNZixqZSSu4iWXc6UcRObJm6iWKThkwwNOjjv7oWjQ_59HIxXyO_WFwavVbY6sVLUptC4Rz7w_DCBpT4aJp9mJy5mjcLT1TaFRi0W2_bsFEy28uPWBvD3je9vfj34MnKbrAKuAmy8cLmGeRVoOVQhgIWAG4AImhumrA-0-SlLDONGKxOxwFOMW2a48qATqWSxZBjoAFT-DY474zB_onFn4Hkg_H57FBqHA49HgQsWSYC-axzTivR86qe9pbDKGPDvunBuYbx4afPCyW21IG7eJXcaJEvXa9G7R1Zsfp_crrcBae3d9ID8-tFsNloK6Jii-Z1ltvKkoZJOMUUbNUVpaZHSGQa-OFkC7KWyhNJ9APZZYSbLjKZyine_5_DzWGZ2Uegz-E6MpZOczrocZCU9BRG09Fu4v0GNxeAY6FlKJyXF9xb5Q3J4Lcx6RFbzIrdPCAUonKaxsQCxDNc2kCFil6EyGqQKGOeQDz3uiFkd7kNgAO5-CZAskLkCmQs2lADmOmTQMlPoJrw6ZvmYisrMisP_tHjXtWjfdXndzygfPZqqP4r5sWh0jABjMw0Dn0k-TGHWcWWk8mTsMQNWspbwkLcoXQJVF5CmZeOBAeODQcDEelCFg0x44pC1Xk1QObpf3MqnaFReKf5OUIe86oqxJV7jy22xxDoRw2RPMbuqToxBHcGQdsjjWuS7bgP8x0tcoUOi3mTojUu_JJ_8rIKms4CHMZL-vp0250i_ZNSfXt3Pl-Tm6GB3R-xs7W0_I7cASld5gjy-RlYX86V9DnB1oV5UOoKSo-tWSn8AqbioVg
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3rixMxEA96gggiPs_qqREEUVi622Szu-CX8856vo4iHty3kOdZ6O7W7hbxn_BvdmYf5bbeCVIKpZN0p5nJ5DdJZoaQF-DGeqUUDxAtB5xpG2TOZ0GmWWLglYUWA5y_HIujE_7xND7tNtyq_rZ7fyTZxjRglqaiHi-tb6d4KsYRT-IAsH6MUWE8Sq-SaxwXPjysFQebUwRQxkl_NHlBr60Y98VgaWoy-P9tp88tVNuXKLdOUpsFanqb3OqQJd1vVeEOueKKu-Rmuy1H22ije-T3127zz1FAqxTd4Tx3TWQLVXSBJdOoLStHS0-XmIjixxpgKFUVUGcAtPPSztc59WqBd7FX8PFM5a4uzS94z62j84IuNzXBKvoTVMLR92J2SK3DZBUY6UnnFcXnlsV9cjJ99-3gKOhKMgQaHIs64AaMUmxUqAUgrZhbwFeGW6bdBAQ78SyzjFujbcLiSDPumOU6Ag3wiqWKTdgDslOUhXtIKEBT71PrAPJYblysBGKJUFsDHikIbkTeDKQjl236DYkJsYcUYFmicCUKF3waCcIdkXEvTGm6dOdYdWMhG7cnFRf0eLXp0T_r8rZvUT8GPDVflKsz2c15Cc6fF-DoKx56mAVcW6UjlUbMgtdqFPzIS9QuiaYEWDOqi4iA8cGkXHI_btIzZjwbkb1BSzABZkju9VN2JqiS0URkgI2TEMjPN2TsidfqCleusU3CsPhSyv7VJsUki-DYjshuq_Kbvw1wHC9ViRFJBpNhMC5DSjH_3iQxZzEXKbL-up8251i_ZNQf_U_jZ-T67HAqP384_vSY3ACc2xTxifge2alXa_cEsGStnzYG4w_a7m43
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Rationale+for+recommending+a+lower+dose+of+primaquine+as+a+Plasmodium+falciparum+gametocytocide+in+populations+where+G6PD+deficiency+is+common&rft.jtitle=Malaria+journal&rft.au=White%2C+Nicholas+J&rft.au=Qiao%2C+Li+Guo&rft.au=Qi%2C+Gao&rft.au=Luzzatto%2C+Lucio&rft.date=2012-12-14&rft.pub=BioMed+Central+Ltd&rft.issn=1475-2875&rft.eissn=1475-2875&rft.volume=11&rft_id=info:doi/10.1186%2F1475-2875-11-418&rft.externalDocID=A534239949
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1475-2875&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1475-2875&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1475-2875&client=summon