A long-term survival case of adult undifferentiated embryonal sarcoma of liver
Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to 10 years) and rarely seen in adults. We present a case of USEL in a 27-year-old woman with no previous history of the disease. Laboratory tes...
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| Published in | World journal of surgical oncology Vol. 10; no. 1; p. 65 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
BioMed Central Ltd
27.04.2012
BioMed Central BMC |
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| Abstract | Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to 10 years) and rarely seen in adults. We present a case of USEL in a 27-year-old woman with no previous history of the disease. Laboratory tests performed on admission showed that the patient had mildly elevated levels of aspartate aminotransferase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and γ-glutamyl transpeptidase. The levels of viral hepatitis and tumor serum markers were all within normal limits. Computed tomography showed a large mass involving the right lobe and the medial segment of the liver. Right trisectionectomy was performed. Microscopically, the tumor was composed of pleomorphic and polynuclear dyskaryotic cells in a myxoid stroma with focal eosinophilic globules and no clear differentiation to muscle. Histological diagnosis showed undifferentiated embryonal sarcoma. Adjuvant therapy with cisplatin, vincristine, doxorubicin, cyclophosphamide, and actinomycin D was initiated. We administered a high dose of etoposide to extract the patient's peripheral blood stem cells and performed radiation therapy and peripheral blood stem cell transplantation. At 5-year follow-up, the patient was alive without any evidence of recurrence. Here, we describe the clinical and histopathological features of USEL as well as the therapeutic options for USEL in adults with this disease. |
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| AbstractList | Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to10 years) and rarely seen in adults. We present a case of USEL in a 27-year-old woman with no previous history of the disease. Laboratory tests performed on admission showed that the patient had mildly elevated levels of aspartate aminotransferase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and γ-glutamyl transpeptidase. The levels of viral hepatitis and tumor serum markers were all within normal limits. Computed tomography showed a large mass involving the right lobe and the medial segment of the liver. Right trisectionectomy was performed. Microscopically, the tumor was composed of pleomorphic and polynuclear dyskaryotic cells in a myxoid stroma with focal eosinophilic globules and no clear differentiation to muscle. Histological diagnosis showed undifferentiated embryonal sarcoma. Adjuvant therapy with cisplatin, vincristine, doxorubicin, cyclophosphamide, and actinomycin D was initiated. We administered a high dose of etoposide to extract the patient's peripheral blood stem cells and performed radiation therapy and peripheral blood stem cell transplantation. At 5-year follow-up, the patient was alive without any evidence of recurrence. Here, we describe the clinical and histopathological features of USEL as well as the therapeutic options for USEL in adults with this disease. Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to 10 years) and rarely seen in adults. We present a case of USEL in a 27-year-old woman with no previous history of the disease. Laboratory tests performed on admission showed that the patient had mildly elevated levels of aspartate aminotransferase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and γ-glutamyl transpeptidase. The levels of viral hepatitis and tumor serum markers were all within normal limits. Computed tomography showed a large mass involving the right lobe and the medial segment of the liver. Right trisectionectomy was performed. Microscopically, the tumor was composed of pleomorphic and polynuclear dyskaryotic cells in a myxoid stroma with focal eosinophilic globules and no clear differentiation to muscle. Histological diagnosis showed undifferentiated embryonal sarcoma. Adjuvant therapy with cisplatin, vincristine, doxorubicin, cyclophosphamide, and actinomycin D was initiated. We administered a high dose of etoposide to extract the patient's peripheral blood stem cells and performed radiation therapy and peripheral blood stem cell transplantation. At 5-year follow-up, the patient was alive without any evidence of recurrence. Here, we describe the clinical and histopathological features of USEL as well as the therapeutic options for USEL in adults with this disease. Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to10 years) and rarely seen in adults. We present a case of USEL in a 27-year-old woman with no previous history of the disease. Laboratory tests performed on admission showed that the patient had mildly elevated levels of aspartate aminotransferase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and [gamma]-glutamyl transpeptidase. The levels of viral hepatitis and tumor serum markers were all within normal limits. Computed tomography showed a large mass involving the right lobe and the medial segment of the liver. Right trisectionectomy was performed. Microscopically, the tumor was composed of pleomorphic and polynuclear dyskaryotic cells in a myxoid stroma with focal eosinophilic globules and no clear differentiation to muscle. Histological diagnosis showed undifferentiated embryonal sarcoma. Adjuvant therapy with cisplatin, vincristine, doxorubicin, cyclophosphamide, and actinomycin D was initiated. We administered a high dose of etoposide to extract the patient's peripheral blood stem cells and performed radiation therapy and peripheral blood stem cell transplantation. At 5-year follow-up, the patient was alive without any evidence of recurrence. Here, we describe the clinical and histopathological features of USEL as well as the therapeutic options for USEL in adults with this disease. Keywords: Long-term survival, Adult undifferentiated embryonal sarcoma of liver, Curable Doc number: 65 Abstract: Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to10 years) and rarely seen in adults. We present a case of USEL in a 27-year-old woman with no previous history of the disease. Laboratory tests performed on admission showed that the patient had mildly elevated levels of aspartate aminotransferase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and γ-glutamyl transpeptidase. The levels of viral hepatitis and tumor serum markers were all within normal limits. Computed tomography showed a large mass involving the right lobe and the medial segment of the liver. Right trisectionectomy was performed. Microscopically, the tumor was composed of pleomorphic and polynuclear dyskaryotic cells in a myxoid stroma with focal eosinophilic globules and no clear differentiation to muscle. Histological diagnosis showed undifferentiated embryonal sarcoma. Adjuvant therapy with cisplatin, vincristine, doxorubicin, cyclophosphamide, and actinomycin D was initiated. We administered a high dose of etoposide to extract the patient's peripheral blood stem cells and performed radiation therapy and peripheral blood stem cell transplantation. At 5-year follow-up, the patient was alive without any evidence of recurrence. Here, we describe the clinical and histopathological features of USEL as well as the therapeutic options for USEL in adults with this disease. Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to10 years) and rarely seen in adults. We present a case of USEL in a 27-year-old woman with no previous history of the disease. Laboratory tests performed on admission showed that the patient had mildly elevated levels of aspartate aminotransferase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and [gamma]-glutamyl transpeptidase. The levels of viral hepatitis and tumor serum markers were all within normal limits. Computed tomography showed a large mass involving the right lobe and the medial segment of the liver. Right trisectionectomy was performed. Microscopically, the tumor was composed of pleomorphic and polynuclear dyskaryotic cells in a myxoid stroma with focal eosinophilic globules and no clear differentiation to muscle. Histological diagnosis showed undifferentiated embryonal sarcoma. Adjuvant therapy with cisplatin, vincristine, doxorubicin, cyclophosphamide, and actinomycin D was initiated. We administered a high dose of etoposide to extract the patient's peripheral blood stem cells and performed radiation therapy and peripheral blood stem cell transplantation. At 5-year follow-up, the patient was alive without any evidence of recurrence. Here, we describe the clinical and histopathological features of USEL as well as the therapeutic options for USEL in adults with this disease. Abstract Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to10 years) and rarely seen in adults. We present a case of USEL in a 27-year-old woman with no previous history of the disease. Laboratory tests performed on admission showed that the patient had mildly elevated levels of aspartate aminotransferase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and γ-glutamyl transpeptidase. The levels of viral hepatitis and tumor serum markers were all within normal limits. Computed tomography showed a large mass involving the right lobe and the medial segment of the liver. Right trisectionectomy was performed. Microscopically, the tumor was composed of pleomorphic and polynuclear dyskaryotic cells in a myxoid stroma with focal eosinophilic globules and no clear differentiation to muscle. Histological diagnosis showed undifferentiated embryonal sarcoma. Adjuvant therapy with cisplatin, vincristine, doxorubicin, cyclophosphamide, and actinomycin D was initiated. We administered a high dose of etoposide to extract the patient’s peripheral blood stem cells and performed radiation therapy and peripheral blood stem cell transplantation. At 5-year follow-up, the patient was alive without any evidence of recurrence. Here, we describe the clinical and histopathological features of USEL as well as the therapeutic options for USEL in adults with this disease. Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to 10 years) and rarely seen in adults. We present a case of USEL in a 27-year-old woman with no previous history of the disease. Laboratory tests performed on admission showed that the patient had mildly elevated levels of aspartate aminotransferase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and γ-glutamyl transpeptidase. The levels of viral hepatitis and tumor serum markers were all within normal limits. Computed tomography showed a large mass involving the right lobe and the medial segment of the liver. Right trisectionectomy was performed. Microscopically, the tumor was composed of pleomorphic and polynuclear dyskaryotic cells in a myxoid stroma with focal eosinophilic globules and no clear differentiation to muscle. Histological diagnosis showed undifferentiated embryonal sarcoma. Adjuvant therapy with cisplatin, vincristine, doxorubicin, cyclophosphamide, and actinomycin D was initiated. We administered a high dose of etoposide to extract the patient's peripheral blood stem cells and performed radiation therapy and peripheral blood stem cell transplantation. At 5-year follow-up, the patient was alive without any evidence of recurrence. Here, we describe the clinical and histopathological features of USEL as well as the therapeutic options for USEL in adults with this disease.Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to 10 years) and rarely seen in adults. We present a case of USEL in a 27-year-old woman with no previous history of the disease. Laboratory tests performed on admission showed that the patient had mildly elevated levels of aspartate aminotransferase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and γ-glutamyl transpeptidase. The levels of viral hepatitis and tumor serum markers were all within normal limits. Computed tomography showed a large mass involving the right lobe and the medial segment of the liver. Right trisectionectomy was performed. Microscopically, the tumor was composed of pleomorphic and polynuclear dyskaryotic cells in a myxoid stroma with focal eosinophilic globules and no clear differentiation to muscle. Histological diagnosis showed undifferentiated embryonal sarcoma. Adjuvant therapy with cisplatin, vincristine, doxorubicin, cyclophosphamide, and actinomycin D was initiated. We administered a high dose of etoposide to extract the patient's peripheral blood stem cells and performed radiation therapy and peripheral blood stem cell transplantation. At 5-year follow-up, the patient was alive without any evidence of recurrence. Here, we describe the clinical and histopathological features of USEL as well as the therapeutic options for USEL in adults with this disease. |
| ArticleNumber | 65 |
| Audience | Academic |
| Author | Nakanishi, Kazuaki Kamachi, Hirofumi Tsuruga, Yosuke Yokoo, Hideki Kakisaka, Tatsuhiko Matsushita, Michiaki Noguchi, Keita Kamiyama, Toshiya |
| AuthorAffiliation | 1 Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan |
| AuthorAffiliation_xml | – name: 1 Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22540346$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/S0168-8278(00)80085-9 10.1097/00042737-200012110-00014 10.1007/s00534-007-1265-y 10.1002/1097-0142(197807)42:1<336::AID-CNCR2820420151>3.0.CO;2-V 10.1002/1097-0142(19931015)72:8<2511::AID-CNCR2820720833>3.0.CO;2-M 10.1016/j.ejso.2004.01.004 10.1053/jpsu.2002.35404 10.1002/cncr.10191 10.1200/JCO.1995.13.3.610 10.1002/1097-0142(19920101)69:1<52::AID-CNCR2820690111>3.0.CO;2-L 10.1002/cncr.23431 10.1111/j.1365-2141.1993.tb03129.x 10.1038/sj.bmt.1705649 |
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| References | Y Tokunaga (990_CR11) 2000; 12 C Zornig (990_CR8) 1992; 39 K Kamezaki (990_CR4) 2007; 39 S Pachera (990_CR5) 2008; 15 CE Urban (990_CR13) 1993; 72 W Crist (990_CR2) 1995; 13 F Lenze (990_CR16) 2008; 112 R Kanamaru (990_CR6) 1991; 21 DY Kim (990_CR15) 2002; 37 T Teshima (990_CR3) 1993; 84 Y Suarez (990_CR10) 2000; 32 G Almogy (990_CR17) 2005; 7 JT Stocker (990_CR1) 1978; 42 NI Walker (990_CR7) 1992; 69 GL Grazi (990_CR9) 1996; 62 G Bisogno (990_CR14) 2002; 94 G Almogy (990_CR12) 2004; 30 18361435 - Cancer. 2008 May 15;112(10):2274-82 8402469 - Cancer. 1993 Oct 15;72(8):2511-6 10707880 - J Hepatol. 2000 Feb;32(2):361 18836810 - J Hepatobiliary Pancreat Surg. 2008;15(5):536-44 15063896 - Eur J Surg Oncol. 2004 May;30(4):421-7 1427575 - Hepatogastroenterology. 1992 Aug;39(4):319-21 1727675 - Cancer. 1992 Jan 1;69(1):52-9 17369863 - Bone Marrow Transplant. 2007 May;39(9):523-7 1942554 - Jpn J Clin Oncol. 1991 Jun;21(3):227-32 11111784 - Eur J Gastroenterol Hepatol. 2000 Nov;12(11):1247-51 12378446 - J Pediatr Surg. 2002 Oct;37(10):1419-23 208754 - Cancer. 1978 Jul;42(1):336-48 8895710 - Am Surg. 1996 Nov;62(11):901-6 7692934 - Br J Haematol. 1993 Aug;84(4):570-3 16259353 - Isr Med Assoc J. 2005 Oct;7(10):672-3 7884423 - J Clin Oncol. 1995 Mar;13(3):610-30 11815984 - Cancer. 2002 Jan 1;94(1):252-7 |
| References_xml | – volume: 32 start-page: 361 year: 2000 ident: 990_CR10 publication-title: J Hepatol doi: 10.1016/S0168-8278(00)80085-9 – volume: 12 start-page: 1247 year: 2000 ident: 990_CR11 publication-title: Eur J Gastroenterol Hepatol doi: 10.1097/00042737-200012110-00014 – volume: 15 start-page: 536 year: 2008 ident: 990_CR5 publication-title: J Hepatobiliary Pancreat Surg doi: 10.1007/s00534-007-1265-y – volume: 42 start-page: 336 year: 1978 ident: 990_CR1 publication-title: Cancer doi: 10.1002/1097-0142(197807)42:1<336::AID-CNCR2820420151>3.0.CO;2-V – volume: 21 start-page: 227 year: 1991 ident: 990_CR6 publication-title: Jpn J Clin Oncol – volume: 72 start-page: 2511 year: 1993 ident: 990_CR13 publication-title: Cancer doi: 10.1002/1097-0142(19931015)72:8<2511::AID-CNCR2820720833>3.0.CO;2-M – volume: 30 start-page: 421 year: 2004 ident: 990_CR12 publication-title: Eur J Surg Oncol doi: 10.1016/j.ejso.2004.01.004 – volume: 37 start-page: 1419 year: 2002 ident: 990_CR15 publication-title: J Pediatr Surg doi: 10.1053/jpsu.2002.35404 – volume: 39 start-page: 319 year: 1992 ident: 990_CR8 publication-title: Brolsch CE: Primary sarcoma of the liver in the adult. Report of five surgically treated patients. Hepatogastroenterology – volume: 94 start-page: 252 year: 2002 ident: 990_CR14 publication-title: Cancer doi: 10.1002/cncr.10191 – volume: 13 start-page: 610 year: 1995 ident: 990_CR2 publication-title: J Clin Oncol doi: 10.1200/JCO.1995.13.3.610 – volume: 69 start-page: 52 year: 1992 ident: 990_CR7 publication-title: Cancer doi: 10.1002/1097-0142(19920101)69:1<52::AID-CNCR2820690111>3.0.CO;2-L – volume: 7 start-page: 672 year: 2005 ident: 990_CR17 publication-title: Isr Med Assoc J – volume: 112 start-page: 2274 year: 2008 ident: 990_CR16 publication-title: Cancer doi: 10.1002/cncr.23431 – volume: 62 start-page: 901 year: 1996 ident: 990_CR9 publication-title: Am Surg – volume: 84 start-page: 570 year: 1993 ident: 990_CR3 publication-title: Br J Haematol doi: 10.1111/j.1365-2141.1993.tb03129.x – volume: 39 start-page: 523 year: 2007 ident: 990_CR4 publication-title: Bone Marrow Transplant doi: 10.1038/sj.bmt.1705649 – reference: 1727675 - Cancer. 1992 Jan 1;69(1):52-9 – reference: 208754 - Cancer. 1978 Jul;42(1):336-48 – reference: 1427575 - Hepatogastroenterology. 1992 Aug;39(4):319-21 – reference: 18361435 - Cancer. 2008 May 15;112(10):2274-82 – reference: 15063896 - Eur J Surg Oncol. 2004 May;30(4):421-7 – reference: 12378446 - J Pediatr Surg. 2002 Oct;37(10):1419-23 – reference: 7692934 - Br J Haematol. 1993 Aug;84(4):570-3 – reference: 11815984 - Cancer. 2002 Jan 1;94(1):252-7 – reference: 1942554 - Jpn J Clin Oncol. 1991 Jun;21(3):227-32 – reference: 7884423 - J Clin Oncol. 1995 Mar;13(3):610-30 – reference: 11111784 - Eur J Gastroenterol Hepatol. 2000 Nov;12(11):1247-51 – reference: 8402469 - Cancer. 1993 Oct 15;72(8):2511-6 – reference: 18836810 - J Hepatobiliary Pancreat Surg. 2008;15(5):536-44 – reference: 16259353 - Isr Med Assoc J. 2005 Oct;7(10):672-3 – reference: 8895710 - Am Surg. 1996 Nov;62(11):901-6 – reference: 10707880 - J Hepatol. 2000 Feb;32(2):361 – reference: 17369863 - Bone Marrow Transplant. 2007 May;39(9):523-7 |
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| Snippet | Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6 to... Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children (aged 6... Doc number: 65 Abstract: Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually... Abstract Undifferentiated embryonal sarcoma of the liver (USEL) is a rare malignant hepatic tumor with a poor prognosis that is usually observed in children... |
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| SubjectTerms | Abdomen Adult Adult undifferentiated embryonal sarcoma of liver Adults Anthracyclines Antineoplastic Combined Chemotherapy Protocols - therapeutic use Aspartate Care and treatment Case Report Cell Differentiation Chemotherapy Cisplatin - administration & dosage Combined Modality Therapy Consent Curable Cyclophosphamide Cyclophosphamide - administration & dosage Dactinomycin - administration & dosage Diagnosis Doxorubicin - administration & dosage Etoposide Female Hematopoietic stem cells Hemorrhage Hepatitis Humans Liver Liver Neoplasms - diagnosis Liver Neoplasms - mortality Liver Neoplasms - therapy Long-term survival Neoplasm Staging Neoplasms, Germ Cell and Embryonal - diagnosis Neoplasms, Germ Cell and Embryonal - mortality Neoplasms, Germ Cell and Embryonal - therapy Patient outcomes Peripheral Blood Stem Cell Transplantation Phosphatases Prognosis Radiation therapy Radiotherapy Radiotherapy Dosage Sarcoma Sarcoma - diagnosis Sarcoma - mortality Sarcoma - therapy Stem cells Surgery Survival Rate Tomography Transplantation Vincristine - administration & dosage Virus diseases |
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| Title | A long-term survival case of adult undifferentiated embryonal sarcoma of liver |
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