Clinical significance of erythropoietin receptor expression in oral squamous cell carcinoma

• Published in: BMC cancer Vol. 12; no. 1; p. 194
• Main Authors: Lin, Yu-Tsai, Chuang, Hui-Ching, Chen, Chang-Han, Armas, Gian Luca, Chen, Han-Ku, Fang, Fu-Min, Huang, Chao-Cheng, Chien, Chih-Yen
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 28.05.2012; BioMed Central; BMC
• Subjects: Adult; Aged; Aged, 80 and over; Analysis; Angiogenesis; Biological markers; Biomarkers; Cancer; Cancer therapies; Carcinoma, Squamous Cell - genetics; Carcinoma, Squamous Cell - mortality; Carcinoma, Squamous Cell - pathology; Care and treatment; Chemotherapy; Classification; Erythropoietin; Female; Gene Expression Regulation, Neoplastic; Head & neck cancer; Hormone receptors; Hospitals; Humans; Hypoxia; Immunohistochemistry; Life sciences; Male; Medical records; Medical research; Medicine, Experimental; Middle Aged; Mouth Neoplasms - genetics; Mouth Neoplasms - mortality; Mouth Neoplasms - pathology; Neoplasm Staging; Oral cancer; Otolaryngology; Prognosis; Proteins; Receptors, Erythropoietin - genetics; Receptors, Erythropoietin - metabolism; Reproductive system; Risk Factors; RNA; Squamous cell carcinoma; Studies; University colleges; Wound healing; Taiwan

Hypoxic tumors are refractory to radiation and chemotherapy. High expression of biomarkers related to hypoxia in head and neck cancer is associated with a poorer prognosis. The present study aimed to evaluate the clinicopathological significance of erythropoietin receptor (EPOR) expression in oral s...