Methylation-mediated deamination of 5-methylcytosine appears to give rise to mutations causing human inherited disease in CpNpG trinucleotides, as well as in CpG dinucleotides - Cooper, David N; Mort, Matthew; Stenson, Peter D; Ball, Edward V; Chuzhanova, Nadia A (Human genomics, 2010)
Keywords: 5-Methylcytosine - metabolism; 5-methylcytosine deamination; CpG dinucleotide; CpNpGp trinucleotide; cytosine methylation; Databases, Nucleic Acid; Deamination; Dinucleoside Phosphates - genetics; DNA Methylation - genetics; Genetic Diseases, Inborn - genetics; human inherited disease; Humans; missense/nonsense mutations; Mutation - genetics; mutation hot-spots; Review; Trinucleotide Repeats - genetics