Systematic review of genome-wide gene expression studies of bipolar disorder

• Published in: BMC psychiatry Vol. 13; no. 1; p. 213
• Main Authors: Seifuddin, Fayaz, Pirooznia, Mehdi, Judy, Jennifer T, Goes, Fernando S, Potash, James B, Zandi, Peter P
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 15.08.2013; BioMed Central
• Subjects: Bioinformatics; Bipolar disorder; Bipolar Disorder - genetics; Bipolar Disorder - metabolism; Brain - metabolism; Brain research; Confidence intervals; Data processing; Emotional disorders; Gene Expression; Genetic aspects; Genetic Predisposition to Disease; Genetic research; Genome-Wide Association Study; Genomes; Genomics; Genotype; Humans; Medical genetics; Medical research; Metallothionein; Psychiatry; Public health; Studies; Systematic review; Twins; United States

Numerous genome-wide gene expression studies of bipolar disorder (BP) have been carried out. These studies are heterogeneous, underpowered and use overlapping samples. We conducted a systematic review of these studies to synthesize the current findings. We identified all genome-wide gene expression...