Exhaled breath condensate pH as a biomarker of COPD severity in ex-smokers

• Published in: Respiratory research Vol. 12; no. 69; p. 67
• Main Authors: Papaioannou, Andriana I, Loukides, Stelios, Minas, Markos, Kontogianni, Konstantina, Bakakos, Petros, Gourgoulianis, Konstantinos I, Alchanatis, Manos, Papiris, Spyros, Kostikas, Konstantinos
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 22.05.2011; BioMed Central; BMC
• Subjects: Aged; Analysis of Variance; Biological markers; Biomarkers - metabolism; Breath Tests; Carbon Dioxide - metabolism; Carbon monoxide; Case-Control Studies; Diagnosis; Ex-smokers; Exhalation; Female; Forced Expiratory Volume; Greece; Health aspects; Humans; Hydrogen-Ion Concentration; Lung - metabolism; Lung - physiopathology; Lung diseases, Obstructive; Male; Middle Aged; Predictive Value of Tests; Pulmonary Diffusing Capacity; Pulmonary Disease, Chronic Obstructive - diagnosis; Pulmonary Disease, Chronic Obstructive - etiology; Pulmonary Disease, Chronic Obstructive - metabolism; Pulmonary Disease, Chronic Obstructive - physiopathology; Residual Volume; Severity of Illness Index; Smokers; Smoking - adverse effects; Smoking Cessation; Smoking Prevention; Total Lung Capacity; Vital Capacity; Greece

Endogenous airway acidification, as assessed by exhaled breath condensate (EBC) pH, is present in patients with stable COPD. The aim of this study was to measure EBC pH levels in a large cohort of COPD patients and to evaluate associations with functional parameters according to their smoking status...