Endurance exercise with reduced muscle glycogen content influences substrate utilization and attenuates acute mTORC1- and autophagic signaling in human type I and type II muscle fibers

• Published in: bioRxiv
• Main Authors: Horwath, O, Cornet, L, Strömlind, H, Moberg, M, Edman, S, Söderlund, K, Checa, A, Ruas, J L, Blomstrand, E
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Laboratory 17.10.2024
• Edition: 1.1
• Subjects: Physiology; autophagy; muscle fiber type; fatty acids; metabolomics; mTORC1
• ISSN: 2692-8205
• DOI: 10.1101/2024.10.14.618241

Exercising with low muscle glycogen content can improve training adaptation, but the mechanisms underlying the muscular adaptation are still largely unknown. In this study, we measured substrate utilization and cell signaling in different muscle fiber types during exercise and investigated a possibl...