A three-way comparative genomic analysis of Mannheimia haemolytica isolates

• Published in: BMC genomics Vol. 11; no. 1; p. 535
• Main Authors: Lawrence, Paulraj K, Kittichotirat, Weerayuth, McDermott, Jason E, Bumgarner, Roger E
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 04.10.2010; BioMed Central; BMC
• Subjects: 60 APPLIED LIFE SCIENCES; Adhesins, Bacterial - genetics; AIDS vaccines; Analysis; Animals; Bacteria; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Base Sequence; BASIC BIOLOGICAL SCIENCES; Beef industry; CATTLE; Cluster Analysis; Colleges & universities; DISEASES; DNA, Bacterial - genetics; DOLLARS; ECONOMICS; EPIDEMIOLOGY; Exotoxins - genetics; Feedlots; FEVER; GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE; Genes; Genes, Bacterial - genetics; Genetic aspects; Genetic markers; GENETICS; Genome, Bacterial - genetics; Genomics; Genomics - methods; Gram-negative bacteria; Health aspects; Inverted Repeat Sequences - genetics; Lipopolysaccharides - genetics; Mannheimia haemolytica - enzymology; Mannheimia haemolytica - genetics; Mannheimia haemolytica - isolation & purification; Mannheimia haemolytica - pathogenicity; MEAT; Metalloendopeptidases - genetics; Microbiology; Multigene Family - genetics; PATHOGENESIS; PATHOGENS; Phylogeny; Physiological aspects; Polymorphism, Single Nucleotide - genetics; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Single nucleotide polymorphisms; Species Specificity; Virulence (Microbiology); Virulence - genetics; United States

Mannhemia haemolytica is a Gram-negative bacterium and the principal etiological agent associated with bovine respiratory disease complex. They transform from a benign commensal to a deadly pathogen, during stress such as viral infection and transportation to feedlots and cause acute pleuropneumonia...