An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92

• Published in: BMC systems biology Vol. 5; no. 151; p. 163
• Main Authors: Charusanti, Pep, Chauhan, Sadhana, McAteer, Kathleen, Lerman, Joshua A, Hyduke, Daniel R, Motin, Vladimir L, Ansong, Charles, Adkins, Joshua N, Palsson, Bernhard O
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.10.2011; BioMed Central
• Subjects: Analysis; Bacteria; Biological markers; Causes of; Control; Genetic aspects; Genome, Bacterial; Genomics; Health aspects; Metabolic Networks and Pathways; Metabolites; Metabolomics - methods; Microbiology; Phenotype; Physiological aspects; Plague; Systems Biology - methods; Yersinia infections; Yersinia pestis; Yersinia pestis - chemistry; Yersinia pestis - genetics; Yersinia pestis - metabolism; United States

Yersinia pestis is a gram-negative bacterium that causes plague, a disease linked historically to the Black Death in Europe during the Middle Ages and to several outbreaks during the modern era. Metabolism in Y. pestis displays remarkable flexibility and robustness, allowing the bacterium to prolife...