Undetectable plasma viral load predicts normal survival in HIV-2-infected people in a West African village

• Published in: Retrovirology Vol. 7; no. 1; p. 46
• Main Authors: van der Loeff, Maarten F Schim, Larke, Natasha, Kaye, Steve, Berry, Neil, Ariyoshi, Koya, Alabi, Abraham, van Tienen, Carla, Leligdowicz, Aleksandra, Sarge-Njie, Ramu, da Silva, Zacharias, Jaye, Assan, Ricard, Dominique, Vincent, Tim, Jones, Sarah Rowland, Aaby, Peter, Jaffar, Shabbar, Whittle, Hilton
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 19.05.2010; BioMed Central; BMC
• Subjects: Adult; Animals; Antiretroviral drugs; Binding sites; CD4 Lymphocyte Count; Cohort analysis; Cohort Studies; Demographic aspects; Epidemiology; Female; Field study; Genomes; Guinea-Bissau; Health aspects; HIV; HIV Antibodies - blood; HIV infection; HIV Infections - mortality; HIV Infections - virology; HIV testing; HIV-2 - isolation & purification; Hospitals; Human immunodeficiency virus; Human immunodeficiency virus 1; Human immunodeficiency virus 2; Humans; Male; Measurement; Methods; Middle Aged; Mortality; Plasma; Plasma - virology; Prognosis; Prospective Studies; Sparsely populated areas; Survival Analysis; Viral Load; Viremia; Guinea-Bissau; West Africa

There have been no previous studies of the long-term survival and temporal changes in plasma viral load among HIV-2 infected subjects. 133 HIV-2 infected and 158 HIV-uninfected subjects from a rural area in North-west Guinea-Bissau, West Africa were enrolled into a prospective cohort study in 1991 a...