Diverse functions of miR-125 family in different cell contexts

• Published in: Journal of hematology and oncology Vol. 6; no. 1; p. 6
• Main Authors: Sun, Yu-Meng, Lin, Kang-Yu, Chen, Yue-Qin
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 15.01.2013; BioMed Central; BMC
• Subjects: Apoptosis; B cells; Biomarker; Biomarkers; Breast cancer; Cell Lineage - genetics; Chromosomes; Development and progression; Disease; DNA binding proteins; Gene Expression Regulation, Neoplastic; Genetic aspects; Genetic transcription; Hematology; Humans; Immune response; Leukemia; Life sciences; Liver cancer; Metastasis; MicroRNA; MicroRNAs - genetics; miR-125 family; Neoplasms - genetics; Oncology; Pathogenesis; Prostate cancer; Proteins; Review; Studies; Therapeutic target; Tumor-promoter; Tumor-suppressor; Tumors; Virus diseases; Wildlife conservation

MicroRNAs (miRNAs) are emerging as a novel class of non-coding RNA molecules that regulate gene expression at a post-transcriptional level. More than 1000 miRNAs have been identified in human cells to date, and they are reported to play important roles in normal cell homeostasis, cell metastasis and...