Population based survival rates for childhood cancer in Britain, 1980-91

Abstract Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Design: Retrospective cohort study. Setting: Great Britain. Subjects—14 973 children with cancer diagnosed during 198...

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Published inBMJ Vol. 309; no. 6969; pp. 1612 - 1616
Main Author Stiller, C A
Format Journal Article
LanguageEnglish
Published England British Medical Journal Publishing Group 17.12.1994
British Medical Association
BMJ Publishing Group Ltd
BMJ Publishing Group LTD
BMJ Group
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ISSN0959-8138
1468-5833
1756-1833
DOI10.1136/bmj.309.6969.1612

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Abstract Abstract Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Design: Retrospective cohort study. Setting: Great Britain. Subjects—14 973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours. Main outcome measures: Actuarial survival rates. Results: For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour. Conclusions: Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years.
AbstractList To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis.OBJECTIVESTo investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis.Retrospective cohort study.DESIGNRetrospective cohort study.Great Britain.SETTINGGreat Britain.14973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours.SUBJECTS14973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours.Actuarial survival rates.MAIN OUTCOME MEASURESActuarial survival rates.For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour.RESULTSFor all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour.Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years.CONCLUSIONSNearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years.
Objectives—To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Design—Retrospective cohort study. Setting—Great Britain. Subjects—14973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours. Main outcome measures—Actuarial survival rates. Results—For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour. Conclusions—Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years.
To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Retrospective cohort study. Great Britain. 14973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours. Actuarial survival rates. For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour. Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years.
Abstract Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Design: Retrospective cohort study. Setting: Great Britain. Subjects—14 973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours. Main outcome measures: Actuarial survival rates. Results: For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour. Conclusions: Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years.
Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Design: Retrospective cohort study. Setting: Great Britain. Subjects—14 973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours. Main outcome measures: Actuarial survival rates. Results: For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour. Conclusions: Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years.
Audience Professional
Author Stiller, C A
AuthorAffiliation Department of Paediatrics, University of Oxford
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  givenname: C A
  surname: Stiller
  fullname: Stiller, C A
  organization: University of Oxford, Department of Paediatrics, Childhood Cancer Research Group, Oxford OX HJ, epidemiologist
BackLink https://www.ncbi.nlm.nih.gov/pubmed/7819936$$D View this record in MEDLINE/PubMed
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Snippet Abstract Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care...
Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a...
Objectives—To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a...
To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population...
Abstract Objectives : To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical...
OBJECTIVES--To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a...
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StartPage 1612
SubjectTerms Adolescent
Cancer
Cancer in children
Child
Child, Preschool
Childhood
Childhood cancer
Children
Ewings sarcoma
Female
Follow-Up Studies
Germ cells
Hodgkin disease
Humans
Infant
Infant, Newborn
Leukemia
Leukemia - mortality
Lymphoma - mortality
Male
Mortality - trends
Neoplasia
Neoplasms - mortality
Neoplasms, Germ Cell and Embryonal - mortality
Nervous System Neoplasms - mortality
Neuroblastoma
Prognosis
Registries
Retrospective Studies
Sarcoma - mortality
Survival Rate
Survival rates
United Kingdom - epidemiology
Title Population based survival rates for childhood cancer in Britain, 1980-91
URI http://bmj.com/content/309/6969/1612.full
https://api.istex.fr/ark:/67375/NVC-M4QZLZL4-W/fulltext.pdf
https://www.jstor.org/stable/29725812
https://www.ncbi.nlm.nih.gov/pubmed/7819936
https://www.proquest.com/docview/1777517651
https://www.proquest.com/docview/76934892
https://pubmed.ncbi.nlm.nih.gov/PMC2541972
Volume 309
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