Population based survival rates for childhood cancer in Britain, 1980-91
Abstract Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Design: Retrospective cohort study. Setting: Great Britain. Subjects—14 973 children with cancer diagnosed during 198...
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Published in | BMJ Vol. 309; no. 6969; pp. 1612 - 1616 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
England
British Medical Journal Publishing Group
17.12.1994
British Medical Association BMJ Publishing Group Ltd BMJ Publishing Group LTD BMJ Group |
Subjects | |
Online Access | Get full text |
ISSN | 0959-8138 1468-5833 1756-1833 |
DOI | 10.1136/bmj.309.6969.1612 |
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Abstract | Abstract Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Design: Retrospective cohort study. Setting: Great Britain. Subjects—14 973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours. Main outcome measures: Actuarial survival rates. Results: For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour. Conclusions: Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years. |
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AbstractList | To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis.OBJECTIVESTo investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis.Retrospective cohort study.DESIGNRetrospective cohort study.Great Britain.SETTINGGreat Britain.14973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours.SUBJECTS14973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours.Actuarial survival rates.MAIN OUTCOME MEASURESActuarial survival rates.For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour.RESULTSFor all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour.Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years.CONCLUSIONSNearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years. Objectives—To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Design—Retrospective cohort study. Setting—Great Britain. Subjects—14973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours. Main outcome measures—Actuarial survival rates. Results—For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour. Conclusions—Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years. To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Retrospective cohort study. Great Britain. 14973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours. Actuarial survival rates. For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour. Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years. Abstract Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Design: Retrospective cohort study. Setting: Great Britain. Subjects—14 973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours. Main outcome measures: Actuarial survival rates. Results: For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour. Conclusions: Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years. Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis. Design: Retrospective cohort study. Setting: Great Britain. Subjects—14 973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours. Main outcome measures: Actuarial survival rates. Results: For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour. Conclusions: Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years. |
Audience | Professional |
Author | Stiller, C A |
AuthorAffiliation | Department of Paediatrics, University of Oxford |
AuthorAffiliation_xml | – name: Department of Paediatrics, University of Oxford |
Author_xml | – sequence: 1 givenname: C A surname: Stiller fullname: Stiller, C A organization: University of Oxford, Department of Paediatrics, Childhood Cancer Research Group, Oxford OX HJ, epidemiologist |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/7819936$$D View this record in MEDLINE/PubMed |
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Copyright | 1994 BMJ Publishing Group Ltd. Copyright 1994 British Medical Journal COPYRIGHT 1994 BMJ Publishing Group Ltd. Copyright: 1994 (c) 1994 BMJ Publishing Group Ltd. |
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Snippet | Abstract Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care... Objectives: To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a... Objectives—To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a... To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population... Abstract Objectives : To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical... OBJECTIVES--To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a... |
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SubjectTerms | Adolescent Cancer Cancer in children Child Child, Preschool Childhood Childhood cancer Children Ewings sarcoma Female Follow-Up Studies Germ cells Hodgkin disease Humans Infant Infant, Newborn Leukemia Leukemia - mortality Lymphoma - mortality Male Mortality - trends Neoplasia Neoplasms - mortality Neoplasms, Germ Cell and Embryonal - mortality Nervous System Neoplasms - mortality Neuroblastoma Prognosis Registries Retrospective Studies Sarcoma - mortality Survival Rate Survival rates United Kingdom - epidemiology |
Title | Population based survival rates for childhood cancer in Britain, 1980-91 |
URI | http://bmj.com/content/309/6969/1612.full https://api.istex.fr/ark:/67375/NVC-M4QZLZL4-W/fulltext.pdf https://www.jstor.org/stable/29725812 https://www.ncbi.nlm.nih.gov/pubmed/7819936 https://www.proquest.com/docview/1777517651 https://www.proquest.com/docview/76934892 https://pubmed.ncbi.nlm.nih.gov/PMC2541972 |
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