Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan

• Published in: Annals of the rheumatic diseases Vol. 74; no. 2; pp. 369 - 374
• Main Authors: Kuo, Chang-Fu, Grainge, Matthew J, See, Lai-Chu, Yu, Kuang-Hui, Luo, Shue-Fen, Valdes, Ana M, Zhang, Weiya, Doherty, Michael
• Format: Journal Article
• Language: English
• Published: England Elsevier Limited 01.02.2015; BMJ Publishing Group
• Series: Extended report
• Subjects: Adolescent; Adult; Age; Age Distribution; Aged; Aged, 80 and over; Bias; Clinical and Epidemiological Research; Cross-Sectional Studies; Disease; Environment; Family medical history; Female; Genetic Predisposition to Disease; Gout - epidemiology; Gout - genetics; Health insurance; Hospitals; Humans; Male; Medical research; Middle Aged; Mortality; Population; Prevalence; Registration; Research centers; Sex Distribution; Socioeconomic Factors; Studies; Taiwan; Young Adult; Taiwan; Epidemiology; Gout; Arthritis
• ISSN: 0003-4967; 1468-2060; 1468-2060
• DOI: 10.1136/annrheumdis-2013-204067

Objective To examine familial aggregation of gout and to estimate the heritability and environmental contributions to gout susceptibility in the general population. Methods Using data from the National Health Insurance (NHI) Research Database in Taiwan, we conducted a nationwide cross-sectional stud...