Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication

• Published in: Current topics in medicinal chemistry Vol. 19; no. 18; p. 1621
• Main Authors: Maeda, Kenji, Das, Debananda, Kobayakawa, Takuya, Tamamura, Hirokazu, Takeuchi, Hiroaki
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2019
• Subjects: Anti-HIV Agents - chemistry; Anti-HIV Agents - pharmacology; Drug Discovery; Drug Resistance, Viral - drug effects; HIV Infections - drug therapy; HIV-1 - drug effects; Humans; AIDS; Reverse transcriptase inhibitors; Combination antiretroviral therapy; HIV; Protease inhibitors; Integrase inhibitors

The history of the human immunodeficiency virus (HIV)/AIDS therapy, which spans over 30 years, is one of the most dramatic stories of science and medicine leading to the treatment of a disease. Since the advent of the first AIDS drug, AZT or zidovudine, a number of agents acting on different drug ta...