Arterial stiffness and central blood pressure, as determined by pulse wave analysis, in rheumatoid arthritis

• Published in: Annals of the rheumatic diseases Vol. 62; no. 5; pp. 414 - 418
• Main Authors: Klocke, R, Cockcroft, J R, Taylor, G J, Hall, I R, Blake, D R
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and European League Against Rheumatism 01.05.2003; BMJ; BMJ Publishing Group Ltd; Elsevier Limited
• Subjects: Adolescent; Adult; AIx; arterial stiffness; Arteries - physiopathology; Arteriosclerosis; Arthritis, Rheumatoid - physiopathology; augmentation index; Biological and medical sciences; Blood pressure; Blood Pressure - physiology; Blood Pressure Determination - methods; C reactive protein; Cardiovascular disease; Cardiovascular diseases; cardiovascular risk; Cohort Studies; Complications and side effects; CRP; DAS; Diastole - physiology; diastolic pressure-time integral; disease activity score; Diseases of the osteoarticular system; DPTI; Elasticity; erythrocyte sedimentation rate; ESR; Extended Report; Female; Glucose; Humans; Inflammation; Inflammatory joint diseases; left ventricular; Male; Measurement; Medical sciences; Middle Aged; Mortality; Patients; Physiological aspects; Pilot Projects; Pulsatile Flow - physiology; pulse wave analysis; pulse wave velocity; PWA; PWV; Rheumatoid arthritis; SPTI; Statistical analysis; Systole - physiology; systolic pressure-time integral; time of return of the reflected wave; VAS; Veins & arteries; visual analogue scale; Human; Immunopathology; Pathophysiology; Mortality; Diseases of the osteoarticular system; Cardiovascular disease; Autoimmune disease; Inflammatory joint disease; Epidemiology; Artery; Morbidity; Vascular disease; Tonometer; Chronic; Correlation analysis; Heart disease; Rheumatoid arthritis; Atherosclerosis; Risk factor; Stiffness; Pressure measurement; Quantitative analysis

Background: Rheumatoid arthritis (RA) is associated with increased cardiovascular mortality for reasons which are insufficiently understood. Chronic inflammation may impair vascular function and lead to an increase of arterial stiffness, an important determinant of cardiovascular risk. Objective: To...