Serum antibodies against genitourinary infectious agents in prostate cancer and benign prostate hyperplasia patients: a case-control study

• Published in: BMC cancer Vol. 11; no. 1; p. 53
• Main Authors: Hrbacek, Jan, Urban, Michael, Hamsikova, Eva, Tachezy, Ruth, Eis, Vaclav, Brabec, Marek, Heracek, Jiri
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 03.02.2011; BioMed Central; BMC
• Subjects: Adult; Aged; Aged, 80 and over; Alphapapillomavirus - immunology; Antibodies; Antibodies, Bacterial - blood; Antibodies, Viral - blood; Blood transfusions; Case-Control Studies; Chlamydia trachomatis - immunology; Complement Fixation Tests; Computer science; Cytomegalovirus - immunology; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Hospitals; Humans; Hypertrophy; Male; Male Urogenital Diseases - immunology; Male Urogenital Diseases - microbiology; Male Urogenital Diseases - virology; Medicine; Middle Aged; Mycoplasma hominis - immunology; Neisseria gonorrhoeae - immunology; Pathology; Prostate; Prostate - pathology; Prostate - surgery; Prostate cancer; Prostatectomy; Prostatic Hyperplasia - blood; Prostatic Hyperplasia - immunology; Prostatic Neoplasms - blood; Prostatic Neoplasms - immunology; Risk factors; Simplexvirus - immunology; Species Specificity; Surgery; Treponema pallidum - immunology; Ureaplasma urealyticum - immunology; Urinary tract infections; Viral antibodies; Viral infections

Infection plays a role in the pathogenesis of many human malignancies. Whether prostate cancer (PCa) - an important health issue in the aging male population in the Western world - belongs to these conditions has been a matter of research since the 1970 s. Persistent serum antibodies are a proof of...