Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing

• Published in: Nutrition & metabolism Vol. 8; no. 1; pp. 68 - 367
• Main Authors: Breen, Leigh, Phillips, Stuart M
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 05.10.2011; BioMed Central; BMC
• Subjects: Aged; dietary protein; dietary recommendations; elderly; exercise; Frailty; Health aspects; ingestion; leucine; messenger RNA; muscle protein; Muscle proteins; muscles; Muscular system; Older people; Physiological aspects; protein intake; protein synthesis; Proteins; Review; Risk factors; Sarcopenia; skeletal muscle; synthetic proteins; wasting syndrome; Canada

Age-related muscle wasting (sarcopenia) is accompanied by a loss of strength which can compromise the functional abilities of the elderly. Muscle proteins are in a dynamic equilibrium between their respective rates of synthesis and breakdown. It has been suggested that age-related sarcopenia is due...