IgG subclasses in smokers with chronic bronchitis and recurrent exacerbations

• Published in: Thorax Vol. 56; no. 6; pp. 445 - 449
• Main Authors: Qvarfordt, I, Riise, G C, Andersson, B A, Larsson, S
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Thoracic Society 01.06.2001; BMJ; BMJ Publishing Group Ltd; BMJ Publishing Group LTD; BMJ Group
• Subjects: Adult; Aged; Airway management; Analysis of Variance; Asymptomatic; Biological and medical sciences; Bronchitis; Bronchitis - blood; Bronchitis - complications; Bronchitis - immunology; Bronchitis/blood/complications/immunology; chronic bronchitis; Chronic Disease; Chronic obstructive pulmonary disease, asthma; Cross-Sectional Studies; Dermatologi och venereologi; Dermatology and Venereal Diseases; Enzyme-Linked Immunosorbent Assay; Female; Health aspects; Humans; IgG Deficiency - etiology; IgG subclasses; Immunodiffusion; Immunoglobulin G; Immunoglobulin G - blood; Immunoglobulin G - classification; Immunoglobulin G/blood/classification; Immunoglobulins; Infections; Male; Measurement; Medical sciences; Middle Aged; Normal distribution; Original; Pneumology; Recurrence; recurrent exacerbations; Risk factors; Smokers; Smoking; Smoking - adverse effects; Smoking - blood; Smoking - immunology; Smoking/adverse effects/blood/immunology; Tobacco; tobacco smoking; United States; United Kingdom > UK; United States > US; Human; Recurrence; Immunoglobulins; Pathophysiology; Respiratory disease; Tobacco smoking; Exploration; Toxicology; Chronic; Risk factor; Bronchus disease; Complication; Bronchitis; Aggravation

BACKGROUND Tobacco smokers have lower serum levels of IgG than non-smokers. IgG subclass deficiency is common in patients with recurrent respiratory infections. Recurrent bronchial infections are common in smokers with chronic bronchitis (CB). We have investigated whether susceptibility to recurrent...