A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus - Olsson, Lina M; Johansson, Åsa C; Gullstrand, Birgitta; Jönsen, Andreas; Saevarsdottir, Saedis; Rönnblom, Lars; Leonard, Dag; Wetterö, Jonas; Sjöwall, Christopher; Svenungsson, Elisabet; Gunnarsson, Iva; Bengtsson, Anders A; et al. (Annals of the rheumatic diseases, 2017)
Keywords: Adult; Alleles; Animal models; Autoimmune diseases; autoimmunity; Case-Control Studies; Clinical Medicine; Disease; Female; Gene Expression; Gene Expression Regulation; Gene polymorphism; Genetic Predisposition to Disease; Genomes; Genotype & phenotype; Genotyping; Humans; Inflammatory diseases; Interferon; Klinisk medicin; Leukocytes (neutrophilic); Lupus; Lupus Erythematosus, Systemic - genetics; Lupus Erythematosus, Systemic - immunology; Lupus Erythematosus, Systemic - metabolism; Lymphocytes; Male; Medical and Health Sciences; Medicin och hälsovetenskap; Mutation; NADPH oxidase complex; NADPH Oxidases - genetics; NCF1; Neutrophils; Neutrophils - immunology; Polymerase chain reaction; Polymorphism, Single Nucleotide; Reactive oxygen species; Reactive Oxygen Species - metabolism; Respiratory Burst - genetics; Rheumatoid arthritis; Rheumatology; Single-nucleotide polymorphism; SLE; Studies; Sweden; Systemic lupus erythematosus; White People - genetics; Sweden; NADPH oxidase complex; NCF1; autoimmunity; SLE; reactive oxygen species