A high resolution RH map of the bovine major histocompatibility complex

• Published in: BMC genomics Vol. 10; no. 182; p. 182
• Main Authors: Brinkmeyer-Langford, Candice L, Childers, Christopher P, Fritz, Krista L, Gustafson-Seabury, Ashley L, Cothran, Marian, Raudsepp, Terje, Womack, James E, Skow, Loren C
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 24.04.2009; BioMed Central; BMC
• Subjects: Animals; Cattle; Cattle - genetics; Chromosome mapping; Chromosomes, Mammalian - genetics; Databases, Nucleic Acid; Genetic aspects; Genetic Markers - genetics; Genome, Human; Genomics - methods; Humans; Major histocompatibility complex; Major Histocompatibility Complex - genetics; Methods; Physiological aspects; Radiation Hybrid Mapping - methods; Reproducibility of Results; Ruminantia; Sequence Tagged Sites; Synteny; United States

The cattle MHC is termed the bovine leukocyte antigen (BoLA) and, along with the MHCs of other ruminants, is unique in its genomic organization. Consequently, correct and reliable gene maps and sequence information are critical to the study of the BoLA region. The bovine genome sequencing project ha...