Promotion of embryonic cortico-cerebral neuronogenesis by miR-124

• Published in: Neural development Vol. 4; no. 1; p. 40
• Main Authors: Maiorano, Nicola Antonio, Mallamaci, Antonello
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 02.11.2009; BioMed Central; BMC
• Subjects: Animals; Cell Cycle - physiology; Cell Movement - physiology; Cells, Cultured; Cerebral cortex; Cerebral Cortex - embryology; Cerebral Cortex - physiology; HeLa Cells; Humans; Mice; Mice, Inbred Strains; MicroRNAs - metabolism; Neurites - physiology; Neurogenesis; Neurogenesis - physiology; Neurons - physiology; Physiological aspects; RNA; Stem Cell Niche - embryology; Stem Cell Niche - physiology; Stem Cells - physiology; Time Factors; Up-Regulation; Italy

Glutamatergic neurons of the murine cerebral cortex are generated within periventricular proliferative layers of the embryonic pallium, directly from apical precursors or indirectly via their basal progenies. Cortical neuronogenesis is the result of different morphogenetic subroutines, including pre...