Skeletal muscle munc18c and syntaxin 4 in human obesity

• Published in: Nutrition & metabolism Vol. 5; no. 1; p. 21
• Main Authors: Bergman, Bryan C, Cornier, Marc-Andre, Horton, Tracy J, Bessesen, Daniel H, Eckel, Robert H
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 24.07.2008; BioMed Central; BMC
• Subjects: Causes of; Health aspects; Insulin resistance; Muscle proteins; Muscles; Obesity; Physiological aspects; Properties; Type 2 diabetes; United States

Animal and cell culture data suggest a critical role for Munc18c and Syntaxin 4 proteins in insulin mediated glucose transport in skeletal muscle, but no studies have been published in humans. We investigated the effect of a 12 vs. 48 hr fast on insulin action and skeletal muscle Munc18c and Syntaxi...