Modularization of biochemical networks based on classification of Petri net t-invariants

• Published in: BMC bioinformatics Vol. 9; no. 1; p. 90
• Main Authors: Grafahrend-Belau, Eva, Schreiber, Falk, Heiner, Monika, Sackmann, Andrea, Junker, Björn H, Grunwald, Stefanie, Speer, Astrid, Winder, Katja, Koch, Ina
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 08.02.2008; BioMed Central; BMC
• Subjects: Algorithms; Computational biology; Computer Simulation; Genes; Models, Biological; Multigene Family - physiology; Proteome - metabolism; Saccharomyces cerevisiae; Signal Transduction - physiology; Transduction; Germany

Structural analysis of biochemical networks is a growing field in bioinformatics and systems biology. The availability of an increasing amount of biological data from molecular biological networks promises a deeper understanding but confronts researchers with the problem of combinatorial explosion....